TLR7 agonist 26
TLR7 agonist 26 (Compound 4) is a potent Toll-like receptor 7 (TLR7) agonist, with an EC50 of 225.5 nM. TLR7 agonist 26 shows immunopotentiating effects.
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- CAS. Nr.: 1641544-09-3
- Formel: C17H19N5O4
- Molecular Weight:357.36
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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TLR7 225.5 nM (EC50) |
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Cell Line
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Type | Value | Description | References |
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| B cell | EC50 |
479.6 nM
Compound: 3b
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Immunostimulatory activity in CFSE-labeled human B cells assessed as TLR7 agonist-induced cell proliferation after 6 days by FACS analysis
Immunostimulatory activity in CFSE-labeled human B cells assessed as TLR7 agonist-induced cell proliferation after 6 days by FACS analysis
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[PMID: 27476423] |
Chemical Information
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CAS. Nr. 1641544-09-3
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Molecular Weight 357.36
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Formel C17H19N5O4
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SMILES
OC1=NC2=C(N)N=C(OCCCC)N=C2N1CC3=CC=C(C(O)=O)C=C3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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