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Cat. No.: HY-153070

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TLR7 agonist 5

TLR7 agonist 5 (compound IIb-11) is an TLR7 agonist with an EC₅₀ value of ~4 nM.

For research use only. We do not sell to patients.

CAS No.: 2380231-67-2
Formula: C₂₈H₃₀N₆O₂
Molecular Weight:482.58

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

TLR7 agonist 5 Chemical Structure

CAS No.: 2380231-67-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

TLR7 agonist 5 (compound IIb-11) is an TLR7 agonist with an EC₅₀ value of ~4 nM^[1].

IC₅₀ & Target^[1]

TLR7

~4 nM (EC₅₀)

All Toll-like Receptor (TLR) Isoforms :

Chemical Information

CAS No. 2380231-67-2
Molecular Weight 482.58
Formula C₂₈H₃₀N₆O₂
SMILES

OC(N1C2=NC(OCC/C=C\CC3=CC(C1)=CC=C3C4=CC=C(C=C4)CNC5CCC5)=N6)=NC2=C6N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Purandare AV, et al. Preparation of macrocyclic purine compounds as toll-like receptor 7 (TLR7) agonists: World Intellectual Property Organization, WO2019209811 A1. 2019-10-31.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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TLR7 agonist 5

All Toll-like Receptor (TLR) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

TLR7 agonist 5 Related Classifications

HY-153070 Related Classifications