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Cat. No.: HY-153071

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TLR7 agonist 6

TLR7 agonist 6 (compound IIb-19) is an TLR7 agonist with an EC₅₀ value of 1.0 nM.

For research use only. We do not sell to patients.

CAS No.: 2380231-86-5
Formula: C₂₇H₃₀N₆O₃
Molecular Weight:486.57

Storage:

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

TLR7 agonist 6 Chemical Structure

CAS No.: 2380231-86-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

TLR7 agonist 6 (compound IIb-19) is an TLR7 agonist with an EC₅₀ value of 1.0 nM^[1].

IC₅₀ & Target^[1]

TLR7

~4 nM (EC₅₀)

All Toll-like Receptor (TLR) Isoforms :

Chemical Information

CAS No. 2380231-86-5
Appearance Solid
Molecular Weight 486.57
Formula C₂₇H₃₀N₆O₃
Color White to off-white
SMILES

OC1=NC2=C(N1CC3=CC(OCCCCO4)=C(C5=CC=C(CNC6CCC6)C=C5)C=C3)N=C4N=C2N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Purandare AV, et al. Preparation of macrocyclic purine compounds as toll-like receptor 7 (TLR7) agonists: World Intellectual Property Organization, WO2019209811 A1. 2019-10-31.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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TLR7 agonist 6

All Toll-like Receptor (TLR) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

TLR7 agonist 6 Related Classifications

HY-153071 Related Classifications