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Cat. No.: HY-109162

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Trazpiroben

Name: Trazpiroben
Brand: MedChemExpress
SKU: HY-109162
Price: 545.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: TAK-906)

Trazpiroben (TAK-906) is a dopamine D2/D3 receptor antagonist used for chronic research of moderate-to-severe gastroparesis.

For research use only. We do not sell to patients.

CAS No.: 1352993-39-5
Formula: C₃₁H₃₉N₃O₄
Molecular Weight:517.66

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Trazpiroben Chemical Structure

CAS No.: 1352993-39-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Clinical Trial
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

Trazpiroben (TAK-906) is a dopamine D2/D3 receptor antagonist used for chronic research of moderate-to-severe gastroparesis^[1].

All Dopamine Receptor Isoforms :

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 1352993-39-5
Molecular Weight 517.66
Formula C₃₁H₃₉N₃O₄
SMILES

O=C(O)C1=CC=CC(CN2CN(C3CCCCC3)C4(CCN(CCCC(C5=CC=CC=C5)=O)CC4)C2=O)=C1
Synonyms

TAK-906
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kuo B, Scimia C, Dukes G, Zhang W, Gupta S, Chen C, Chuang E, Camilleri M. Randomised clinical trial: safety, pharmacokinetics and pharmacodynamics of trazpiroben (TAK-906), a dopamine D2 /D3 receptor antagonist, in patients with gastroparesis. Aliment Ph [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- Clinical Trial
Chemical Information
Purity & Documentation
References

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Trazpiroben

All Dopamine Receptor Isoforms