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  3. Infection Inflammation or Immune System Disease
  4. Parasitic Infection Autoimmune Disease Pathogens Infection
  5. Plasmodium Infection Systemic Lupus Erythematosus Sepsis
  6. TSI-13-48

TSI-13-48 (HY-182409) is a TLR inhibitor with IC50 values of 3.02, 22.3, 26.5, and 26.6 μM against TLR9, TLR7, TLR2, and TLR4, respectively. TSI-13-48 can be used in research related to systemic lupus erythematosus, polymicrobial sepsis, and cerebral malaria.

For research use only. We do not sell to patients.

TSI-13-48

TSI-13-48 Chemical Structure

CAS No. : 2254006-84-1

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TSI-13-48 Related Antibodies

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Description

TSI-13-48 (HY-182409) is a TLR inhibitor with IC50 values of 3.02, 22.3, 26.5, and 26.6 μM against TLR9, TLR7, TLR2, and TLR4, respectively. TSI-13-48 can be used in research related to systemic lupus erythematosus, polymicrobial sepsis, and cerebral malaria[1].

Molecular Weight

498.57

Formula

C29H30N4O4
CAS No.
SMILES

COC1=CC=C(C=C1)C2=CC(C3=CC=C(OCCN4CCCCC4)C=C3)=NN2C(C=C5)=CC=C5[N+]([O-])=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TSI-13-48 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TSI-13-482254006-84-1estrogen receptorToll-like receptorTLR2polymicrobial sepsisTLR7TLR4TLR9RAW264.7 macrophage cellscerebral malariasystemic lupus erythematosusInhibitorinhibitorinhibit

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