2. Others PI3K/Akt/mTOR Cell Cycle/DNA Damage
  3. ATM/ATR Isotope-Labeled Compounds
  4. Tuvusertib-d3

Tuvusertib-d3  (Synonyms: M1774-d3; ATR inhibitor 1-d3)

Cat. No.: HY-111451S
Handling Instructions Technical Support

Tuvusertib-d3 (M1774-d3) is the deuterium labeled Tuvusertib (HY-111451). Tuvusertib (M1774; ATR inhibitor 1) is a selective and orally active ATR inhibitor with a Ki value below 1 μΜ.

For research use only. We do not sell to patients.

Tuvusertib-d<sub>3</sub>

Tuvusertib-d3 Chemical Structure

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Other Forms of Tuvusertib-d3:

Tuvusertib-d3 Related Antibodies

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Description

Tuvusertib-d3 (M1774-d3) is the deuterium labeled Tuvusertib (HY-111451). Tuvusertib (M1774; ATR inhibitor 1) is a selective and orally active ATR inhibitor with a Ki value below 1 μΜ.

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tuvusertib-d3 Related Antibodies
Molecular Weight

373.33

Formula

C16H9D3F2N8O
Unlabeled CAS
SMILES

O=C(NC1=C(C(F)=CN=C1)C2=CN=CN2C([2H])([2H])[2H])C3=C4N=CC(F)=CN4N=C3N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Tuvusertib-d3 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tuvusertib-d3M1774-d3 ATR inhibitor 1-d3ATM/ATRIsotope-Labeled CompoundsAtaxia telangiectasia mutatedATM and RAD3 relatedInhibitorinhibitorinhibit

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