BMS-884775
BMS-884775 is a selective and orally active P2Y1 antagonist with an IC50 of 0.1 nM for the human P2Y1 receptor. BMS-884775 has a similar efficacy in preventing arterial thrombosis to Clopidogrel (HY-15283) and Prasugrel (HY-15284), but treatment with BMS-884775 results in shorter bleeding time and lower bleeding risk. BMS-884775 can be used in research related to antiplatelet and arterial thrombosis-associated diseases.
For research use only. We do not sell to patients.
- CAS No.: 1557206-59-3
- Formula: C36H35ClF2N6O2S
- Molecular Weight:689.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All P2Y Receptor Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
P2Y1 Receptor |
Chemical Information
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CAS No. 1557206-59-3
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Molecular Weight 689.22
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Formula C36H35ClF2N6O2S
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SMILES
O=C(NC1=NC2=CC=C(Cl)N=C2S1)NC3=CC=CC=C3N4CC5(CCN(CC(C)(C)C)CC5)C6=C4C(O)=CC(F)=C6C7=CC=C(F)C=C7
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)