Botryodiplodin
Botryodiplodin is a mycotoxin isolated from Penicillium roqueforti. Botryodiplodin inhibits the growth of some Gram-positive and Gram-negative bacteria and can also induce DNA-protein cross-links in mammalian cells, inhibiting the synthesis of DNA, RNA, and protein.
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- CAS No.: 27098-03-9
- Formula: C7H12O3
- Molecular Weight:144.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
All DNA/RNA Synthesis Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 27098-03-9
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Molecular Weight 144.17
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Formula C7H12O3
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SMILES
O=C(C)[C@H]1[C@H](C(OC1)O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Purity & Documentation
References
[1]. Moulé Y, et al. DNA-protein cross-linking by the mycotoxin, botryodiplodin, in mammalian cells[J]. Carcinogenesis, 1982, 3(2): 211-214. [Content Brief]
[2]. Moulé Y, et al. Mutagenicity of the mycotoxin botryodiplodin in the Salmonella typhimurium/microsomal activation test[J]. Environmental Mutagenesis, 1981, 3(3): 287-291. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Botryodiplodin Related Classifications
HY-121234 Related Classifications
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