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Cizutamig

(Synonyms: CND-106; EMB-06)
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Based on 1 Customer Validation

Cizutamig (CND-106) is a bispecific T-cell engager targeting BCMA and CD3. Cizutamig exhibits immunostimulatory and anti-tumor activities. Cizutamig can be used in research related to relapsed or refractory multiple myeloma and systemic lupus erythematosus.

For research use only. We do not sell to patients.

  • Purity : 99.00%
  • CAS No.: 2919209-65-5
  • Molecular Weight:241.429 kDa
  • Storage:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Cizutamig
  • Experimental Validation Results for Cizutamig
  • Experimental Validation Results for Cizutamig
  • Experimental Validation Results for Cizutamig
  • Cizutamig Chemical Structure
    Cizutamig Chemical Structure
CAS No.: 2919209-65-5
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Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Cizutamig Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Top Publications Citing

Use of MCE Products

All TNF Receptor Isoforms

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Assay Types
  • 1/16

    VK-CK-VH-CH1-h-CH2-CH3_L-kappa_Fab-G1-kappa

  • 1/16

    Immobilized CD3 epsilon Protein, Human (HEK293, HY-P70506) can bind Cizutamig. The ED50 for this effect is 5.73 ng/mL.

  • 1/16

    Loaded Cizutamig on ProA biosensor, can bind BCMA/TNFRSF17 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78070) with an affinity constant of 8.191E-11 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells labeling CD3E with Cizutamig (HY-P990980, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Cizutamig Chemical Structure
    1/16
  • Cizutamig
  • Immobilized CD3 epsilon Protein, Human (HEK293, HY-P70506) can bind Cizutamig. The ED50 for this effect is 5.73 ng/mL.
  • Loaded Cizutamig on ProA biosensor, can bind BCMA/TNFRSF17 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78070) with an affinity constant of 8.191E-11 M as determined in BLI assay.
  • Flow cytometric analysis of 1X106 Jurkat cells labeling CD3E with Cizutamig (HY-P990980, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • VK-CK-VH-CH1-h-CH2-CH3_L-kappa_Fab-G1-kappa