Dopal (purity>80%)
Dopal (purity>80%) is a metabolite and aldehyde neurotoxin of Dopamine (HY-B0451). Dopal (purity>80%) exhibits cytotoxicity, induces α-synuclein oligomerization and aggregation, and is closely associated with the pathogenesis of Parkinson's disease. Dopal (purity>80%) can be used in research related to Parkinson's disease.
For research use only. We do not sell to patients.
- CAS No.: 5707-55-1
- Formula: C8H8O3
- Molecular Weight:152.15
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All α-synuclein Isoforms
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Biological Activity
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α-synuclein Aggregation |
Chemical Information
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CAS No. 5707-55-1
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Molecular Weight 152.15
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Formula C8H8O3
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SMILES
O=CCC1=CC=C(O)C(O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Masato A, et al. DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson's disease. NPJ Parkinsons Dis. 2023 Mar 25;9(1):42. [Content Brief]
[2]. Bloch DN, et al. Scavenging neurotoxic aldehydes using lysine carbon dots. Nanoscale Adv. 2023 Jan 19;5(5):1356-1367. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)