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Semorinemab

(Synonyms: RG 6100; RO7105705; MTAU-9937A)
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Based on 1 Customer Validation

Semorinemab (RG 6100) is an anti-Tau humanized IgG4 monoclonal antibody, targets the N-terminal portion of the Tau protein (amino acid residues 6-23). Semorinemab binds with human Tau with a Kd value of 3.8 nM. Semorinemab can be used for the research of Alzheimer's Disease.

For research use only. We do not sell to patients.

  • Purity: 99.36%
  • CAS No.: 2159141-27-0
  • Molecular Weight:145.1 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Semorinemab
  • Experimental Validation Results for Semorinemab
  • Experimental Validation Results for Semorinemab
  • Semorinemab Chemical Structure
    Semorinemab Chemical Structure
CAS No.: 2159141-27-0
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Semorinemab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Immobilized Human Tau Protein (His Tag) can bind Semorinemab. The EC50 for this effect is 4.02 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5X106 SHSY5Y cells with Semorinemab (HY-P99399, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa, Isotype Control (HY-P99003, blue) was used as the isotype control.

  • Semorinemab Chemical Structure
    1/16
  • Semorinemab
  • Immobilized Human Tau Protein (His Tag) can bind Semorinemab. The EC50 for this effect is 4.02 ng/mL.
  • Flow cytometric analysis of 1.5X106 SHSY5Y cells with Semorinemab (HY-P99399, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa, Isotype Control (HY-P99003, blue) was used as the isotype control.