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Cat. No.: HY-145569

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Fipravirimat

(Synonyms: GSK3640254)

Fipravirimat is a potent HIV-1 inhibitor. Fipravirimat has the potential for HIV and AIDS research.

For research use only. We do not sell to patients.

CAS No.: 1818867-24-1
Formula: C₄₃H₆₇FN₂O₄S
Molecular Weight:727.07

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Fipravirimat Chemical Structure

CAS No.: 1818867-24-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Fipravirimat is a potent HIV-1 inhibitor. Fipravirimat has the potential for HIV and AIDS research^[1].

IC₅₀ & Target^[1]

HIV-1

All HIV Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
MT2	CC₅₀	13.3 μM Compound: 41	Cytotoxicity in human MT2 cells assessed as reduction in cell viability Cytotoxicity in human MT2 cells assessed as reduction in cell viability	[PMID: 36044257]
MT2	CC₅₀	13.3 μM Compound: 5	Cytotoxicity against human MT2 cells assessed as reduction in cell viability Cytotoxicity against human MT2 cells assessed as reduction in cell viability	[PMID: 36441509]
MT2	CC₅₀	15.6 μM Compound: 4; GSK3640254	Cytotoxicity against human MT2 cells assessed as reduction in cell viability Cytotoxicity against human MT2 cells assessed as reduction in cell viability	[PMID: 36441509]
MT2	CC₅₀	15.6 μM Compound: 9; GSK3640254	Cytotoxicity in human MT2 cells assessed as reduction in cell viability Cytotoxicity in human MT2 cells assessed as reduction in cell viability	[PMID: 36044257]

Chemical Information

CAS No. 1818867-24-1
Molecular Weight 727.07
Formula C₄₃H₆₇FN₂O₄S
SMILES

O=S(CCN1CCN[C@]23[C@@]([C@@H](CC3)C(C)=C)([H])[C@]4([H])[C@@](CC2)([C@]5([C@]([C@@]6([C@@](C(C)(C(C7=CC[C@](C(O)=O)(CF)CC7)=CC6)C)([H])CC5)C)([H])CC4)C)C)(CC1)=O
Synonyms

GSK3640254
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jie Chen, et al. C-3 and c-17 modified triterpenoids as hiv-1 inhibitors. WO2017134596A1.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Fipravirimat

All HIV Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Fipravirimat Related Classifications

HY-145569 Related Classifications