country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-182553

Copy Link Print Information

USP30-IN-2

USP30-IN-2, a fused pyrroline, is an USP30 inhibitor with an IC₅₀ <0.1 μM. USP30-IN-2 is expected to promote mitophagy and restore mitochondrial health. USP30-IN-2 can be used for research on Parkinson's disease.

For research use only. We do not sell to patients.

CAS No.: 2414580-72-4
Formula: C₂₂H₁₉N₅O₂
Molecular Weight:385.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

USP30-IN-2 Chemical Structure

CAS No.: 2414580-72-4

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

USP30

<0.1 μM (IC₅₀)

All Deubiquitinase Isoforms :

In Vitro

USP30-IN-2 (Compound 13-a) exhibits an IC₅₀ value of less than 0.1 μM against USP30 (0.2 nM) in Ubiquitin-Rhodamine 110 assay^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2414580-72-4
Molecular Weight 385.42
Formula C₂₂H₁₉N₅O₂
SMILES

O=C(C1=CC(C2=C(C=CC=C2)OC3=CC=CC=C3)=NN1)N[C@@H]4[C@@]5([H])[C@](N(C4)C#N)([H])C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Buckmelter AJ, et al. Fused pyrrolines which act as ubiquitin-specific protease 30 (usp30) inhibitors. United States, WO2020072964 A.2020-07-29.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote

Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

USP30-IN-2

All Deubiquitinase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

USP30-IN-2 Related Classifications

HY-182553 Related Classifications