2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Valilactone

Valilactone  (Synonyms: (-)-Valilactone)

Cat. No.: HY-124258 Purity: 98.2%
COA
SDS
Handling Instructions Technical Support

Valilactone is a potent and effective inhibitor of esterase, produced by actinomycetes.

For research use only. We do not sell to patients.

Valilactone

Valilactone Chemical Structure

CAS No. : 113276-96-3

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500 μg In-stock

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Based on 1 publication(s) in Google Scholar

Valilactone Related Antibodies

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Human Endogenous Metabolite Microbial Metabolite

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Description

Valilactone is a potent and effective inhibitor of esterase, produced by actinomycetes[1].

Cellular Effect
Cell Line Type Value Description References
MDA-MB-435 IC50
10.5 μM
Compound: valilactone
Cytotoxicity against human MDA-MB-435 cells after 48 hrs by Cell titer assay
Cytotoxicity against human MDA-MB-435 cells after 48 hrs by Cell titer assay
[PMID: 18710210]
Molecular Weight

397.55

Formula

C22H39NO5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCCCCC[C@H]1[C@@H](OC1=O)C[C@H](CCCCC)OC([C@H](C(C)C)NC=O)=O
Structure Classification
Initial Source

actinomycetes
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (62.89 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5154 mL 12.5770 mL 25.1541 mL
5 mM 0.5031 mL 2.5154 mL 5.0308 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99%

SDS (252 KB)

COA (249 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5154 mL 12.5770 mL 25.1541 mL 62.8852 mL
5 mM 0.5031 mL 2.5154 mL 5.0308 mL 12.5770 mL
10 mM 0.2515 mL 1.2577 mL 2.5154 mL 6.2885 mL
15 mM 0.1677 mL 0.8385 mL 1.6769 mL 4.1923 mL
20 mM 0.1258 mL 0.6289 mL 1.2577 mL 3.1443 mL
25 mM 0.1006 mL 0.5031 mL 1.0062 mL 2.5154 mL
30 mM 0.0838 mL 0.4192 mL 0.8385 mL 2.0962 mL
40 mM 0.0629 mL 0.3144 mL 0.6289 mL 1.5721 mL
50 mM 0.0503 mL 0.2515 mL 0.5031 mL 1.2577 mL
60 mM 0.0419 mL 0.2096 mL 0.4192 mL 1.0481 mL
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Valilactone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Valilactone113276-96-3(-)-ValilactoneEndogenous MetaboliteesteraseactinomycetesInhibitorinhibitorinhibit

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