1. Anti-infection
  2. HIV
  3. Valopicitabine

Valopicitabine (Synonyms: NM283)

Cat. No.: HY-108060
Handling Instructions

Valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine, acts as a promising antiviral agent for reasearch of chronic HCV infection.

For research use only. We do not sell to patients.

Valopicitabine Chemical Structure

Valopicitabine Chemical Structure

CAS No. : 640281-90-9

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Description

Valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine, acts as a promising antiviral agent for reasearch of chronic HCV infection[1].

IC50 & Target

HCV[1]

In Vivo

Valopicitabine (NM 283) has potent antiviral activity against chronic hepatitis C virus genotype-1 in the chimpanzee[1].
Valopicitabine exhibits moderate Cmax (3.62 ug/mL) and terminal elimination half-lives (T1/2 0.64 h) following oral administration (100 mg/kg) in Sprague-Dawley rats[2].

Molecular Weight

356.37

Formula

C₁₅H₂₄N₄O₆

CAS No.

640281-90-9

SMILES

C[[email protected]]([[email protected]@](N(C=CC(N)=N1)C1=O)([H])O[[email protected]@H]2CO)([[email protected]@H]2OC([[email protected]@H](N)C(C)C)=O)O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

ValopicitabineNM283NM 283NM-283HIVHuman immunodeficiency virusHepatitisCVirusNucleosidesProdrugsInhibitorinhibitorinhibit

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Valopicitabine
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