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Cat. No.: HY-120440

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VT-ME6

VT-ME6 is a selective SphK2 inhibitor with a K_i of 8 µM. VT-ME6 can be used in the research of inflammatory diseases.

For research use only. We do not sell to patients.

CAS No.: 1353880-00-8
Formula: C₂₅H₄₄IN
Molecular Weight:485.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (261 KB)

VT-ME6 Chemical Structure

CAS No.: 1353880-00-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

VT-ME6 is a selective SphK2 inhibitor with a K_i of 8 µM. VT-ME6 can be used in the research of inflammatory diseases^[1].

IC₅₀ & Target^[1]

SphK2

8 μM (Ki)

All SphK Isoforms :

SphK1
SphK2

Chemical Information

CAS No. 1353880-00-8
Molecular Weight 485.53
Formula C₂₅H₄₄IN
SMILES

CCC[N+](C)(C)[C@H]1CC[C@H](C2=CC=C(CCCCCCCC)C=C2)CC1.[I-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (261 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Vogt D, et al. Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism. Med Res Rev. 2017 Jan;37(1):3-51. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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