VUF-6884
VUF-6884 (Compound 7j) is a histamine receptor (Histamine Receptor) ligand with activity toward human H4R and H1R. Its pEC50 and pKi values against human H4R are 7.70 and 7.55, respectively, while those against human H1R are 8.17 and 8.11, respectively. VUF-6884 competitively binds to the orthosteric binding site of human H4R to displace histamine, and exhibits inverse agonist activity at human H1R.
For research use only. We do not sell to patients.
- CAS No.: 3455-10-5
- Formula: C18H18ClN3O
- Molecular Weight:327.81
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Histamine Receptor Isoforms
More
Biological Activity
Chemical Information
-
CAS No. 3455-10-5
-
Molecular Weight 327.81
-
Formula C18H18ClN3O
-
SMILES
ClC1=CC=C2N=C(C=3C=CC=CC3OC2=C1)N4CCN(C)CC4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)