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Cat. No.: HY-N1056

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Yunnancoronarin A

(Synonyms: Zerumbetol)

Yunnancoronarin A (Zerumbetol) can be isolated from Hedychium forrestii. Yunnancoronarin A is cytotoxic, with IC₅₀ values of 11.08 and 2.19 μM against lung adenocarcinoma cells A549 and leukemia cells K562, respectively.

For research use only. We do not sell to patients.

CAS No.: 162762-93-8
Formula: C₂₀H₂₈O₂
Molecular Weight:300.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Yunnancoronarin A Chemical Structure

CAS No.: 162762-93-8

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Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
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Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
A-431	IC₅₀	29.02 μg/mL Compound: 3	Cytotoxicity against human A431 cells Cytotoxicity against human A431 cells	[PMID: 19027298]
A549	IC₅₀	46.56 μg/mL Compound: 3	Cytotoxicity against human A549 cells Cytotoxicity against human A549 cells	[PMID: 19027298]
CHO	IC₅₀	17.89 μg/mL Compound: 3	Cytotoxicity against CHO cells Cytotoxicity against CHO cells	[PMID: 19027298]
COLO 205	IC₅₀	27.14 μg/mL Compound: 3	Cytotoxicity against human COLO205 cells Cytotoxicity against human COLO205 cells	[PMID: 19027298]
HeLa	IC₅₀	6.58 μg/mL Compound: 4	Cytotoxicity against human HeLa cells after 48 hrs by SRB assay Cytotoxicity against human HeLa cells after 48 hrs by SRB assay	[PMID: 26351042]
MCF7	IC₅₀	28.05 μg/mL Compound: 3	Cytotoxicity against human MCF7 cells Cytotoxicity against human MCF7 cells	[PMID: 19027298]
RAW264.7	IC₅₀	0.56 μg/mL Compound: 4	Inhibition of LPS and IFN-gamma-stimulated nitric oxide production in mouse RAW264.7 cells after 18 hrs by Griess method Inhibition of LPS and IFN-gamma-stimulated nitric oxide production in mouse RAW264.7 cells after 18 hrs by Griess method	[PMID: 26351042]
SGC-7901	IC₅₀	6.21 μg/mL Compound: 4	Cytotoxicity against human SGC7901 cells after 48 hrs by SRB assay Cytotoxicity against human SGC7901 cells after 48 hrs by SRB assay	[PMID: 26351042]

Chemical Information

CAS No. 162762-93-8
Molecular Weight 300.44
Formula C₂₀H₂₈O₂
SMILES

O[C@@H]1CC([C@H](/C=C/C2=COC=C2)[C@@]3(C)CCCC(C)(C)[C@]13[H])=C
Synonyms

Zerumbetol
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhao Q, et al. Cytotoxicity of labdane-type diterpenoids from Hedychium forrestii. Chem Pharm Bull (Tokyo). 2008 Feb;56(2):210-2. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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