2. Cell Cycle/DNA Damage PI3K/Akt/mTOR
  3. ATM/ATR
  4. YY2201

YY2201 is a highly potent and selective ATR inhibitor with an IC50 of 8 nM. YY2201 shows >200-fold more selective for ATR than mTOR. YY2201 inhibits tumor progression in broad-spectrum cancer types (such as lung cancer).

For research use only. We do not sell to patients.

YY2201

YY2201 Chemical Structure

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YY2201 Related Antibodies

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Description

YY2201 is a highly potent and selective ATR inhibitor with an IC50 of 8 nM. YY2201 shows >200-fold more selective for ATR than mTOR. YY2201 inhibits tumor progression in broad-spectrum cancer types (such as lung cancer)[1].

Clinical Trial
Molecular Weight

583.60

Formula

C29H29N9O5
SMILES

CC1=NN(C2=CC=CN=C2)C(C)=C1C3=CC(N4C[C@@H](CC5)O[C@@H]5C4)=NC6=C(C7=CC=NN7)C=NN36.OC(/C=C/C(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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YY2201 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

YY2201YY 2201YY-2201ATM/ATRAtaxia telangiectasia mutatedATM and RAD3 relatedATR inhibitorbroad-spectrum cancer typesInhibitorinhibitorinhibit

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