2. Others Autophagy Anti-infection Apoptosis
  3. Autophagy Bacterial Apoptosis Isotope-Labeled Compounds
  4. Zoledronic acid-d3

Zoledronic acid-d3  (Synonyms: Zoledronate-d3; CGP 42446-d3; CGP42446A-d3; ZOL 446-d3)

Cat. No.: HY-13777S1
Handling Instructions Technical Support

Zoledronic acid-d3 (Zoledronate-d3) is the deuterium labeled Zoledronic acid (HY-13777). Zoledronic Acid (Zoledronate) is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic Acid inhibits the differentiation and apoptosis of osteoclasts. Zoledronic Acid also has anti-cancer effects.

For research use only. We do not sell to patients.

Zoledronic acid-d<sub>3</sub>

Zoledronic acid-d3 Chemical Structure

CAS No. : 1134798-26-7

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Other Forms of Zoledronic acid-d3:

Zoledronic acid-d3 Related Antibodies

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Description

Zoledronic acid-d3 (Zoledronate-d3) is the deuterium labeled Zoledronic acid (HY-13777). Zoledronic Acid (Zoledronate) is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic Acid inhibits the differentiation and apoptosis of osteoclasts. Zoledronic Acid also has anti-cancer effects[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Zoledronic acid-d3 Related Antibodies
Molecular Weight

275.11

Formula

C5H7D3N2O7P2
CAS No.
Unlabeled CAS
SMILES

OC(P(O)(O)=O)(P(O)(O)=O)CN1C([2H])=C([2H])N=C1[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O : 4.17 mg/mL (15.16 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6349 mL 18.1745 mL 36.3491 mL
5 mM 0.7270 mL 3.6349 mL 7.2698 mL
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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.6349 mL 18.1745 mL 36.3491 mL 90.8727 mL
5 mM 0.7270 mL 3.6349 mL 7.2698 mL 18.1745 mL
10 mM 0.3635 mL 1.8175 mL 3.6349 mL 9.0873 mL
15 mM 0.2423 mL 1.2116 mL 2.4233 mL 6.0582 mL
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Zoledronic acid-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Zoledronic acid-d31134798-26-7Zoledronate-d3 CGP 42446-d3 CGP42446A-d3 ZOL 446-d3AutophagyBacterialApoptosisIsotope-Labeled CompoundsInhibitorinhibitorinhibit

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