1. Metabolic Enzyme/Protease
  2. Mineralocorticoid Receptor
    Endogenous Metabolite
  3. 18-Oxocortisol

18-Oxocortisol 

Cat. No.: HY-113151 Purity: ≥98.0%
Handling Instructions

18-Oxocortisol is a derivative of cortisol that is produced by aldosterone synthase (CYP11B2). 18-Oxocortisol is a naturally occurring mineralocorticoid agonist. 18-Oxocortisol is a biomarker in adrenal vein sampling.

For research use only. We do not sell to patients.

18-Oxocortisol Chemical Structure

18-Oxocortisol Chemical Structure

CAS No. : 2410-60-8

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Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

18-Oxocortisol is a derivative of cortisol that is produced by aldosterone synthase (CYP11B2). 18-Oxocortisol is a naturally occurring mineralocorticoid agonist. 18-Oxocortisol is a biomarker in adrenal vein sampling[1][2][3].

In Vivo

Administration of 18-oxocortisol to rats induces a mineralocorticoid-type hypertension with hypokalemia, cardiac and renal enlargement and cardiovascular lesions. Administration of 18-oxocortisol to sheep also causes a rapid increase in blood pressure. However, the doses required for increasing blood pressure are high[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

376.44

Formula

C21H28O6

CAS No.
SMILES
Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥98.0%

References
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18-Oxocortisol
Cat. No.:
HY-113151
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