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Cat. No.: HY-N8385

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19,20-Epoxycytochalasin C

Name: 19,20-Epoxycytochalasin C
Brand: MedChemExpress
SKU: HY-N8385
Price: 389.00 USD
Availability: InStock
Rating: 5 (1 reviews)

19,20-Epoxycytochalasin C, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin C shows potent in vitro antiplasmodial activity and phytotoxicity.

For research use only. We do not sell to patients.

CAS No.: 189351-79-9
Formula: C₃₀H₃₇NO₇
Molecular Weight:523.62

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (279 KB)

19,20-Epoxycytochalasin C Chemical Structure

CAS No.: 189351-79-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

19,20-Epoxycytochalasin C, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin C shows potent in vitro antiplasmodial activity and phytotoxicity^[1].

IC₅₀ & Target

Plasmodium

Microbial Metabolite

All Parasite Isoforms :

All Endogenous Metabolite Isoforms :

In Vitro

19,20-Epoxycytochalasin C shows moderate toxicity to cell line SK-MEL with an IC₅₀ of 8.02 µM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

In Vivo

Evaluation of in vivo antimalarial activity of 19,20-Epoxycytochalasin C in a mouse model at 100 mg/kg dose shows that this compound has weak suppressive antiplasmodial activity and is toxic to animals^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 189351-79-9
Molecular Weight 523.62
Formula C₃₀H₃₇NO₇
SMILES

CC(O[C@H]([C@@]1([H])[C@@]([C@@](O)(C2=O)C)([H])O1)[C@@]([C@](/C=C/C[C@@H]2C)([H])[C@@H]3O)(C(N4)=O)[C@](C(C)=C3C)([H])[C@@H]4CC5=CC=CC=C5)=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Microorganisms
Xylaria obovata
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (279 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mallika Kumarihamy, et al. Antiplasmodial and Cytotoxic Cytochalasins from an Endophytic Fungus, Nemania sp. UM10M, Isolated from a Diseased Torreya taxifolia Leaf. Molecules. 2019 Feb 21;24(4):777. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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