Δ4-Dafachronic Acid-d3
Δ4-Dafachronic Acid-d3 is deuterium labeled Δ4-Dafachronic acid (HY-131492). Δ4‑Dafachronic acid is an endogenous steroid hormone, an agonist of the DAF‑12 nuclear receptor, and a key ligand for the vitamin D receptor (VDR). Δ4‑Dafachronic acid promotes the active escape developmental trajectory in Austrofundulus limnaeus embryos even under diapause‑inducing conditions. Δ4‑Dafachronic acid is suitable for research on the developmental biology.
For research use only. We do not sell to patients.
- Formula: C27H39D3O3
- Molecular Weight:417.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 23017-97-2
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Molecular Weight 417.64
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Formula C27H39D3O3
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SMILES
O=C1CC[C@]2(C(CC[C@@]3([C@@]2(CC[C@]4([C@]3(CC[C@@]4([C@H](C)CCCC(C(O)=O)C([2H])([2H])[2H])[H])[H])C)[H])[H])=C1)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Romney ALT, et al. Temperature-dependent vitamin D signaling regulates developmental trajectory associated with diapause in an annual killifish. Proc Natl Acad Sci U S A. 2018;115(50):12763-12768. [Content Brief]
[2]. Warnke M, et al. Functional Characterization of Three Specific Acyl-Coenzyme A Synthetases Involved in Anaerobic Cholesterol Degradation in Sterolibacterium denitrificans Chol1S. Appl Environ Microbiol. 2018;84(7):e02721-17. Published 2018 Mar 19. [Content Brief]
[3]. Niciura SCM, et al. In vitro culture of parasitic stages of Haemonchus contortus. Rev Bras Parasitol Vet. 2023;32(1):e010122. Published 2023 Jan 13. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)