5-Chlorouridine
5-Chlorouridine, a ribonucleoside, is an inhibitor of RNase A (Ki = 44.5 μM) and eosinophil derived neurotoxin (EDN) (Ki = 1080.1 μM; IC50 = 1462.8 μM). 5-Chlorouridine can be used for the researches of inflammatory disorders and hypereosinophilic syndromes.
For research use only. We do not sell to patients.
- CAS No.: 2880-89-9
- Formula: C9H11ClN2O6
- Molecular Weight:278.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
5-Chlorouridine (Compound V) inhibits bovine pancreatic ribonuclease A with a Ki of 44.5 ± 4.6 μM and recombinant human eosinophil derived neurotoxin with an IC50 of 1462.8 ± 109.8 μM and a Ki of 1080.1 ± 160.0 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2880-89-9
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Molecular Weight 278.65
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Formula C9H11ClN2O6
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SMILES
O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(Cl)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)