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Cat. No.: HY-131827

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5-Chlorouridine

5-Chlorouridine, a ribonucleoside, is an inhibitor of RNase A (K_i = 44.5 μM) and eosinophil derived neurotoxin (EDN) (K_i = 1080.1 μM; IC₅₀ = 1462.8 μM). 5-Chlorouridine can be used for the researches of inflammatory disorders and hypereosinophilic syndromes.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2880-89-9
화학식: C₉H₁₁ClN₂O₆
분자량:278.65

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

5-Chlorouridine Chemical Structure

CAS No.: 2880-89-9

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All DNA/RNA Synthesis Isoforms :

In Vitro

5-Chlorouridine (Compound V) inhibits bovine pancreatic ribonuclease A with a K_i of 44.5 ± 4.6 μM and recombinant human eosinophil derived neurotoxin with an IC₅₀ of 1462.8 ± 109.8 μM and a K_i of 1080.1 ± 160.0 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2880-89-9
분자량 278.65
화학식 C₉H₁₁ClN₂O₆
SMILES

O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(Cl)=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Chatzileontiadou DS, et al. Triazole double-headed ribonucleosides as inhibitors of eosinophil derived neurotoxin. Bioorg Chem. 2015;63:152-165. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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