8-Hydroxydihydrochelerythrine
8-Hydroxydihydrochelerythrine is a benzophenanthridine alkaloid-derived, selective and competitive AChE inhibitor (IC50=0.61 μM) isolated from the roots of Zanthoxylum nitidum (Roxb.) DC. 8-Hydroxydihydrochelerythrine increases the content of acetylcholine in the synapses of cholinergic neurons and enhances cholinergic neurotransmission. 8-Hydroxydihydrochelerythrine is applicable to the research of neurodegenerative diseases with dementia such as Alzheimer's disease.
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- CAS No.: 4070-42-2
- Formule: C21H19NO5
- Masse moléculaire:365.38
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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AChE 0.61 μM (IC50) |
BChE 34.6 μM (IC50) |
AChE 0.25 μM (Ki) |
Chemical Information
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CAS No. 4070-42-2
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Masse moléculaire 365.38
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Formule C21H19NO5
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SMILES
OC1C2=C(C3=CC=C4C=C5OCOC5=CC4=C3N1C)C=CC(OC)=C2OC
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
8-Hydroxydihydrochelerythrine Related Classifications
HY-N18289 Related Classifications
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