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製品番号: HY-N2794

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9-Hydroxy-α-lapachone

Name: 9-Hydroxy-α-lapachone
Brand: MedChemExpress
SKU: HY-N2794
Price: 420.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(別名: α-Dihydrocaryopterone)

9-Hydroxy-α-lapachone (α-Dihydrocaryopterone) is a natural phenol, exhibits potent inhibitory effects with an IC₅₀ of 4.64 µM on LPS-induced NO production in RAW 264.7 cells.

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CAS 番号: 22333-58-0
分子式: C₁₅H₁₄O₄
分子量:258.27

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

9-Hydroxy-α-lapachone 構造式

CAS 番号: 22333-58-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

9-Hydroxy-α-lapachone (α-Dihydrocaryopterone) is a natural phenol, exhibits potent inhibitory effects with an IC₅₀ of 4.64 µM on LPS-induced NO production in RAW 264.7 cells^[1].

NO Synthase アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
HBL-100	GI₅₀	3.4 μM Compound: 3a, 9-hydroxy-alpha-lapachone	Growth inhibition of human HBL100 cells by SRB assay Growth inhibition of human HBL100 cells by SRB assay	[PMID: 22560628]
HeLa	GI₅₀	1.8 μM Compound: 3a, 9-hydroxy-alpha-lapachone	Growth inhibition of human HeLa cells by SRB assay Growth inhibition of human HeLa cells by SRB assay	[PMID: 22560628]
SW1573	GI₅₀	19 μM Compound: 3a, 9-hydroxy-alpha-lapachone	Growth inhibition of human SW1573 cells by SRB assay Growth inhibition of human SW1573 cells by SRB assay	[PMID: 22560628]
WiDr	GI₅₀	14 μM Compound: 3a, 9-hydroxy-alpha-lapachone	Growth inhibition of human WiDr cells by SRB assay Growth inhibition of human WiDr cells by SRB assay	[PMID: 22560628]

化学情報

CAS 番号 22333-58-0
分子量 258.27
分子式 C₁₅H₁₄O₄
SMILES

O=C(C1=C2OC(C)(C)CC1)C3=C(C2=O)C(O)=CC=C3
別名

α-Dihydrocaryopterone
Structure Classification
- Quinones
- Naphthalene Quinones
- Phenols
- Monophenols
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (269 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Byeong Min Park, et al. Naphthoquinones from Catalpa ovata and their inhibitory effects on the production of nitric oxide. Arch Pharm Res. 2010 Mar;33(3):381-5. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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