9-Hydroxy-α-lapachone
9-Hydroxy-α-lapachone (α-Dihydrocaryopterone) is a natural phenol, exhibits potent inhibitory effects with an IC50 of 4.64 µM on LPS-induced NO production in RAW 264.7 cells.
For research use only. We do not sell to patients.
- CAS No.: 22333-58-0
- Formula: C15H14O4
- Molecular Weight:258.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HBL-100 | GI50 |
3.4 μM
Compound: 3a, 9-hydroxy-alpha-lapachone
|
Growth inhibition of human HBL100 cells by SRB assay
Growth inhibition of human HBL100 cells by SRB assay
|
[PMID: 22560628] |
| HeLa | GI50 |
1.8 μM
Compound: 3a, 9-hydroxy-alpha-lapachone
|
Growth inhibition of human HeLa cells by SRB assay
Growth inhibition of human HeLa cells by SRB assay
|
[PMID: 22560628] |
| SW1573 | GI50 |
19 μM
Compound: 3a, 9-hydroxy-alpha-lapachone
|
Growth inhibition of human SW1573 cells by SRB assay
Growth inhibition of human SW1573 cells by SRB assay
|
[PMID: 22560628] |
| WiDr | GI50 |
14 μM
Compound: 3a, 9-hydroxy-alpha-lapachone
|
Growth inhibition of human WiDr cells by SRB assay
Growth inhibition of human WiDr cells by SRB assay
|
[PMID: 22560628] |
Chemical Information
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CAS No. 22333-58-0
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Molecular Weight 258.27
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Formula C15H14O4
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SMILES
O=C(C1=C2OC(C)(C)CC1)C3=C(C2=O)C(O)=CC=C3
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Synonyms
α-Dihydrocaryopterone
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)