AKT-IN-2
AKT-IN-2 is a potent, selective and orally bioavailable AKT inhibitor with an IC50 of 5 nM for AKT1.
For research use only. We do not sell to patients.
- CAS No.: 1295514-91-8
- Formula: C25H34F3N7O
- Molecular Weight:505.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Akt1 5 nM (IC50) |
P70S6K 399 nM (IC50) |
PKA 84 nM (IC50) |
PKCβ2 3.98 μM (IC50) |
RSK1 568 nM (IC50) |
pGSK3β 92 nM (IC50) |
Chemical Information
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CAS No. 1295514-91-8
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Molecular Weight 505.58
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Formula C25H34F3N7O
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SMILES
O=C1C[C@@H](C)C2=C(N3CCC(C4=NC(CCC(F)(F)F)=CN4CCN5CCCC5)CC3)N=CN=C2N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)