1. MAPK/ERK Pathway
    Autophagy
  2. p38 MAPK
    Autophagy
  3. AZD7624

AZD7624 

Cat. No.: HY-103672
Handling Instructions

AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity.

For research use only. We do not sell to patients.

AZD7624 Chemical Structure

AZD7624 Chemical Structure

CAS No. : 1095004-78-6

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Description

AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity.

IC50 & Target

p38[1]

In Vitro

AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity. AZD7624 inhibits LPS-induced TNFα in human mononuclear cells, in whole blood as well as in alveolar macrophages in vitro, with pIC50s of 8.4, 8.1, and 9.0[1].

Clinical Trial
Molecular Weight

491.56

Formula

C₂₇H₃₀FN₅O₃

CAS No.

1095004-78-6

SMILES

O=C(NC1CC1)C2=CC(N3C(C(NC4(C5=CC=CC=C5OCCNC)CC4)=NC=C3)=O)=C(C)C(F)=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

AZD7624AZD 7624AZD-7624p38 MAPKAutophagyInhibitorinhibitorinhibit

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