1. Protein Tyrosine Kinase/RTK
    JAK/STAT Signaling
  2. EGFR
  3. EGFR-IN-3

EGFR-IN-3 

Cat. No.: HY-19815 Purity: 99.94%
Handling Instructions

EGFR-IN-3 is an epidermal growth factor receptor (EGFR) inhibitor.

For research use only. We do not sell to patients.

EGFR-IN-3 Chemical Structure

EGFR-IN-3 Chemical Structure

CAS No. : 1660963-42-7

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 257 In-stock
Estimated Time of Arrival: December 31
5 mg USD 220 In-stock
Estimated Time of Arrival: December 31
10 mg USD 350 In-stock
Estimated Time of Arrival: December 31
25 mg USD 650 In-stock
Estimated Time of Arrival: December 31
50 mg USD 900 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1400 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Description

EGFR-IN-3 is an epidermal growth factor receptor (EGFR) inhibitor.

IC50 & Target

EGFR.

Molecular Weight

530.57

Formula

C₂₉H₂₈F₂N₆O₂

CAS No.

1660963-42-7

SMILES

OCCN1CCN(C2=C(F)C(F)=C(NC3=NC=C4C(C(C5=CC(NC(C=C)=O)=CC=C5)=CC=C4)=N3)C=C2)CC1

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (235.60 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8848 mL 9.4238 mL 18.8477 mL
5 mM 0.3770 mL 1.8848 mL 3.7695 mL
10 mM 0.1885 mL 0.9424 mL 1.8848 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (3.92 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (3.92 mM); Clear solution

*All of the co-solvents are provided by MCE.
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Product Name:
EGFR-IN-3
Cat. No.:
HY-19815
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