1. MAPK/ERK Pathway
    Stem Cell/Wnt
  2. ERK
  3. ERK2 IN-1

ERK2 IN-1 

Cat. No.: HY-112300
Handling Instructions

ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM.

For research use only. We do not sell to patients.

ERK2 IN-1 Chemical Structure

ERK2 IN-1 Chemical Structure

CAS No. : 1093061-47-2

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Description

ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM[1].

IC50 & Target[1]

ERK2

7 nM (IC50)

In Vitro

ERK1/2 IN-1 (Compound 28) maintains good ERK enzymatic activity (ERK IC50=7 nM) and cellular activity in BRAF/KRAS mutant wildtype cancer cell lines (HT-29/Caspase IC50=118/80 nM)[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

647.76

Formula

C₃₆H₃₄FN₇O₂S

CAS No.

1093061-47-2

SMILES

FC1=CC=C(C2=NNC3=C2C=C(NC([[email protected]@]4(SC)CN(CC(N5CCC(C6=CC=C(C7=NC=CC=N7)C=C6)=CC5)=O)CC4)=O)C=C3)C=C1

Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
ERK2 IN-1
Cat. No.:
HY-112300
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ERK2 IN-1

Cat. No.: HY-112300