1. GPCR/G Protein
    Neuronal Signaling
  2. Adrenergic Receptor
  3. Dopexamine hydrochloride

Dopexamine hydrochloride (Synonyms: FPL60278AR)

Cat. No.: HY-U00205
Handling Instructions

Dopexamine hydrochloride is a β2 adrenergic receptor agonist.

For research use only. We do not sell to patients.

Dopexamine hydrochloride Chemical Structure

Dopexamine hydrochloride Chemical Structure

CAS No. : 86484-91-5

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Description

Dopexamine hydrochloride is a β2 adrenergic receptor agonist.

IC50 & Target

β2 adrenergic receptor[1]

In Vitro

Dopexamine is a dopamine analogue with agonist activity at β2 and dopaminergic receptors. Dopexamine can attenuate the systemic inflammatory response, reduce tissue leukocyte infiltration, and protect against organ injury at doses that do not alter global hemodynamics or regional microvascular flow[1]. Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects. Dopexamine reduces the systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress, without substantially changing systemic hemodynamics, either blood pressure or stroke volume[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

429.42

Formula

C₂₂H₃₄Cl₂N₂O₂

CAS No.

86484-91-5

SMILES

[H]Cl.[H]Cl.OC1=CC=C(CCNCCCCCCNCCC2=CC=CC=C2)C=C1O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

DopexamineFPL60278ARAdrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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Dopexamine hydrochloride
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HY-U00205
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