1. Metabolic Enzyme/Protease
  2. Acyltransferase
  3. FR-190809

FR-190809 is a potent, nonadrenotoxic, orally efficacious acyl-CoA:cholesterol O-acyltransferase (ACAT) inhibitor, with an IC50 of 45 nM.

For research use only. We do not sell to patients.

FR-190809 Chemical Structure

FR-190809 Chemical Structure

CAS No. : 215589-63-2

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Description

FR-190809 is a potent, nonadrenotoxic, orally efficacious acyl-CoA:cholesterol O-acyltransferase (ACAT) inhibitor, with an IC50 of 45 nM[1].

IC50 & Target

IC50: (ACAT)[1]

In Vitro

FR-190809 inhibits foam cell formation with an IC50 of 215 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

603.73

Formula

C29H34FN3O6S2

CAS No.
SMILES

O=C(NC1=C(S(=O)(C)=O)C=C(C)N=C1S(=O)(C)=O)N(C2CCCCCC2)CC3=CC=C(OC4=CC=C(F)C=C4)C=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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FR-190809 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
FR-190809
Cat. No.:
HY-122078
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