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Hypaconitine 

Cat. No.: HY-N0267 Purity: >98.0%
Handling Instructions

Hypaconitine, an active and highly toxic constituent derived from Aconitum species, is widely used to treat rheumatism.

For research use only. We do not sell to patients.

Hypaconitine Chemical Structure

Hypaconitine Chemical Structure

CAS No. : 6900-87-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 172 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
10 mg USD 156 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
50 mg USD 468 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Hypaconitine, an active and highly toxic constituent derived from Aconitum species, is widely used to treat rheumatism. IC50 value: Target: In vitro: The present study investigated the metabolism of hypaconitine in vitro using male human liver microsomes. The primary contributors toward HA metabolism were CYP3A4 and 3A5, with secondary contributions by CYP2C19, 2D6 and CYP2E1 [1]. In vivo:

References
Molecular Weight

615.71

Formula

C₃₃H₄₅NO₁₀

CAS No.

6900-87-4

SMILES

CO[[email protected]@H](CC1)C23[[email protected]@](C[[email protected]@]4(O)[[email protected]@H]5OC(C6=CC=CC=C6)=O)([H])[[email protected]@]5([H])[[email protected]](OC(C)=O)([[email protected]@H](O)[[email protected]@H]4OC)C7C2N(C)C[[email protected]@]1(COC)[[email protected]@]3([H])[[email protected]]7OC

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
Hypaconitine
Cat. No.:
HY-N0267
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