1. Biochemical Assay Reagents
  2. IPTG

IPTG (Synonyms: Isopropyl β-D-thiogalactoside)

Cat. No.: HY-15921 Purity: >98.0%
Handling Instructions

IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator.

For research use only. We do not sell to patients.

IPTG Chemical Structure

IPTG Chemical Structure

CAS No. : 367-93-1

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
500 mg USD 50 In-stock
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1 g USD 60 In-stock
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5 g USD 70 In-stock
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10 g USD 110 In-stock
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25 g USD 150 In-stock
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50 g   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

Top Publications Citing Use of Products

Publications Citing Use of MCE IPTG

    IPTG purchased from MCE. Usage Cited in: Int J Mol Sci. 2018 May 7;19(5). pii: E1393.

    Screening of thymidylate synthase (TYMS) overexpression conditions.
    • Biological Activity

    • Purity & Documentation

    • References

    • Customer Review

    Description

    IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator.

    In Vitro

    IPTG uptake by E. coli can be independent of the action of lactose permease, since other transport pathways are also involved. At low concentration, IPTG enters cells through lactose permease, but at high concentrations (typically used for protein induction), IPTG can enter the cells independently of lactose permease[1].

    Molecular Weight

    238.30

    Formula

    C₉H₁₈O₅S

    CAS No.

    367-93-1

    SMILES
    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    DMSO : ≥ 60 mg/mL (251.78 mM)

    *"≥" means soluble, but saturation unknown.

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 4.1964 mL 20.9820 mL 41.9639 mL
    5 mM 0.8393 mL 4.1964 mL 8.3928 mL
    10 mM 0.4196 mL 2.0982 mL 4.1964 mL
    *Please refer to the solubility information to select the appropriate solvent.
    In Vivo:
    • 1.

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

      Solubility: ≥ 2.67 mg/mL (11.20 mM); Clear solution

    • 2.

      Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

      Solubility: ≥ 2.67 mg/mL (11.20 mM); Clear solution

    • 3.

      Add each solvent one by one:  10% DMSO    90% corn oil

      Solubility: ≥ 2.67 mg/mL (11.20 mM); Clear solution

    *All of the co-solvents are provided by MCE.
    References

    Purity: >98.0%

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    • Molarity Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    × = ×
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    Keywords:

    IPTGIsopropyl β-D-thiogalactosideOthersInhibitorinhibitorinhibit

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    Product name:
    IPTG
    Cat. No.:
    HY-15921
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