Isocitric acid
Based on 2 publication(s) in Google Scholar
Isocitric acid is an endogenous metabolite present in Saliva and Cellular_Cytoplasm that can be used for the research of Alzheimer's Disease, Lewy Body Dementia and Anoxia.
For research use only. We do not sell to patients.
- Purity: 99.14%
- CAS No.: 320-77-4
- Formula: C6H8O7
- Molecular Weight:192.12
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Isocitric acid
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 320-77-4
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Appearance Solid
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Molecular Weight 192.12
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Formula C6H8O7
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Color White to off-white
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SMILES
OC(C(O)=O)C(C(O)=O)CC(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Nature
2025 Jul;643(8070):192-200. PMID: 39695227 -
Cell Death Dis
m5C-methylated lncRNA NR_033928 promotes gastric cancer proliferation by stabilizing GLS mRNA to promote glutamine metabolism reprogramming. [Abstract]2023 Aug 15;14(8):520. PMID: 37582794
Solvent & Solubility
H2O : 100 mg/mL (520.51 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720. [Content Brief]
[2]. Tsuruoka M, et al. Capillary electrophoresis-mass spectrometry-based metabolome analysis of serum and saliva from neurodegenerative dementia patients. Electrophoresis. 2013 Oct;34(19):2865-72. [Content Brief]
[3]. Zupke C, et al. Intracellular flux analysis applied to the effect of dissolved oxygen on hybridomas. Appl Microbiol Biotechnol. 1995 Dec;44(1-2):27-36. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.2051 mL | 26.0254 mL | 52.0508 mL | 130.1270 mL |
| 5 mM | 1.0410 mL | 5.2051 mL | 10.4102 mL | 26.0254 mL | |
| 10 mM | 0.5205 mL | 2.6025 mL | 5.2051 mL | 13.0127 mL | |
| 15 mM | 0.3470 mL | 1.7350 mL | 3.4701 mL | 8.6751 mL | |
| 20 mM | 0.2603 mL | 1.3013 mL | 2.6025 mL | 6.5064 mL | |
| 25 mM | 0.2082 mL | 1.0410 mL | 2.0820 mL | 5.2051 mL | |
| 30 mM | 0.1735 mL | 0.8675 mL | 1.7350 mL | 4.3376 mL | |
| 40 mM | 0.1301 mL | 0.6506 mL | 1.3013 mL | 3.2532 mL | |
| 50 mM | 0.1041 mL | 0.5205 mL | 1.0410 mL | 2.6025 mL | |
| 60 mM | 0.0868 mL | 0.4338 mL | 0.8675 mL | 2.1688 mL | |
| 80 mM | 0.0651 mL | 0.3253 mL | 0.6506 mL | 1.6266 mL | |
| 100 mM | 0.0521 mL | 0.2603 mL | 0.5205 mL | 1.3013 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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