1. Immunology/Inflammation
  2. Toll-like Receptor (TLR)
  3. LHC-165

LHC-165 

Cat. No.: HY-111786 Purity: 98.17%
Handling Instructions

LHC-165 is a TLR7 agonist. Has potential to treat solid tumors.

For research use only. We do not sell to patients.

LHC-165 Chemical Structure

LHC-165 Chemical Structure

CAS No. : 1258595-14-0

Size Price Stock Quantity
1 mg USD 395 In-stock
Estimated Time of Arrival: December 31
5 mg USD 790 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1200 In-stock
Estimated Time of Arrival: December 31
50 mg USD 3100 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

LHC-165 is a TLR7 agonist. Has potential to treat solid tumors[1][2].

IC50 & Target[1]

TLR7

 

Clinical Trial
Molecular Weight

603.55

Formula

C₂₉H₃₂F₂N₃O₇P

CAS No.

1258595-14-0

SMILES

NC1=C2C(C=C(CCC3=CC=C(OCCOCCC(F)(F)P(O)(O)=O)C=C3C)C=N2)=C4C(C=C(CCC(O)=O)C=C4)=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

1M NaOH : 50 mg/mL (82.84 mM; ultrasonic and adjust pH to 12 with NaOH)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6569 mL 8.2843 mL 16.5686 mL
5 mM 0.3314 mL 1.6569 mL 3.3137 mL
10 mM 0.1657 mL 0.8284 mL 1.6569 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

LHC-165LHC165LHC 165Toll-like Receptor (TLR)Inhibitorinhibitorinhibit

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LHC-165
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HY-111786
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