Sponge

Jaspamycin (Standard) is the analytical standard of Jaspamycin (HY-111759). This product is intended for research and analytical applications. Jaspamycin (7-CN-7-C-Ino) is a potent activator of PKA, binding to the R site (PKAR), with an EC₅₀ of 6.5 nM and K_d of 8 nM in Trypanosoma brucei. Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα. Anti-parasite activity.

Azumamide E is a HDAC inhibitor, with an IC₅₀ of 0.064 μM against HDAC, 1.22 μM against HDAC1, and 2.28 μM against HDAC4. Azumamide E inhibits HDAC activity in nuclear extracts of leukemia cells and cervical adenocarcinoma cells. Azumamide E suppresses angiogenesis. Azumamide E is applicable for research on leukemia, cervical adenocarcinoma, and anti-angiogenesis.

Methyl 6-bromo-1H-indole-3-carboxylate (Standard) is the analytical standard of Methyl 6-bromo-1H-indole-3-carboxylate (HY-W052289). This product is intended for research and analytical applications. Methyl 6-bromo-1H-indole-3-carboxylate is a marine-derived natural product with antitumor activity. Methyl 6-bromo-1H-indole-3-carboxylate showed growth inhibition against Staphylococcus epidermidis, exhibiting weak or moderate minimum inhibitory concentrations (MICs).

Methyl 2-(6-bromo-1H-indol-3-yl)acetate (Standard) is the analytical standard of Methyl 2-(6-bromo-1H-indol-3-yl)acetate (HY-W035305). This product is intended for research and analytical applications. Methyl 2-(6-bromo-1H-indol-3-yl)acetate is a natural product derived from marine sources, specifically isolated from Pseudosuberites hyalinus.

Methyl 5-bromo-1H-pyrrole-2-carboxylate (Standard) is the analytical standard of Methyl 5-bromo-1H-pyrrole-2-carboxylate (HY-W006646). This product is intended for research and analytical applications. Methyl 5-bromo-1H-pyrrole-2-carboxylate (Compound 7) is a pyrrole that can be isolated from marine sponges Lissodendotyx sp.

Batzelladine L is a potent Plasmodium falciparum inhibitor (IC₅₀= 0.4 μM). Batzelladine L shows moderate cytotoxicity to HepG2 cells (CC₅₀= 14 μM) with antimalarial properties. Batzelladine L is promising for research of antimalarial agents.

Baculiferins A is a DOPA-derived pyrrole alkaloid. Baculiferins A can be isolated from the Chinese marine sponge Iotrochota baculifera. Baculiferins A have anti-HIV activity.

Bengamide B is an alkaloid with anti-tumor and anti-inflammatory activities. Bengamide B reduces the phosphorylation level of IκBα, thereby blocking the activation of NF-κB. Bengamide B inhibits the proliferation of tumor cells. Bengamide B can be used in research related to inflammatory diseases and cancers.

Sceptrin dihydrochloride is a compound isolated from the sea sponge Agelas sceptrum that is an antimicrobial agent.

Aerothionin is an antibiotic with potent antimicrobial efficacy against bacteria and fungi. Aerothionin exhibits antitumor efficacy against adrenal pheochromocytomas and extra-adrenal paragangliomas (PPGLs).

Calyxamine B is a piperidine alkaloid that can be isolated from Calyx podatypa.