1. Membrane Transporter/Ion Channel
  2. Sodium Channel

PF-05241328 

Cat. No.: HY-103623
Handling Instructions

PF-05241328 is a potent and selective inhibitor of human Nav1.7 voltage-dependent sodium channels (Nav1.7), with an IC50 of 31 nM.

For research use only. We do not sell to patients.

PF-05241328 Chemical Structure

PF-05241328 Chemical Structure

CAS No. : 1387633-03-5

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5 mg USD 190 Get quote
10 mg USD 290 Get quote
50 mg USD 890 Get quote

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

PF-05241328 is a potent and selective inhibitor of human Nav1.7 voltage-dependent sodium channels (Nav1.7), with an IC50 of 31 nM.

IC50 & Target

IC50: 31 nM (Nav1.7)[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2888 mL 11.4440 mL 22.8880 mL
5 mM 0.4578 mL 2.2888 mL 4.5776 mL
10 mM 0.2289 mL 1.1444 mL 2.2888 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

436.91

Formula

C₁₉H₂₁ClN₄O₄S

CAS No.

1387633-03-5

SMILES

O=C(C1=CC2=C(N(C3=CC(Cl)=C(OCC(C)C)N=C3)N=C2C)C=C1)NS(=O)(C)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
PF-05241328
Cat. No.:
HY-103623
Quantity:

PF-05241328

Cat. No.: HY-103623