1. Membrane Transporter/Ion Channel
  2. Sodium Channel
  3. PF-05241328

PF-05241328 

Cat. No.: HY-103623 Purity: 99.50%
COA Handling Instructions

PF-05241328 is a potent and selective inhibitor of human Nav1.7 voltage-dependent sodium channels (Nav1.7), with an IC50 of 31 nM.

For research use only. We do not sell to patients.

PF-05241328 Chemical Structure

PF-05241328 Chemical Structure

CAS No. : 1387633-03-5

Size Price Stock Quantity
5 mg USD 310 In-stock
Estimated Time of Arrival: December 31
10 mg USD 480 In-stock
Estimated Time of Arrival: December 31
25 mg USD 850 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1350 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2160 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

PF-05241328 is a potent and selective inhibitor of human Nav1.7 voltage-dependent sodium channels (Nav1.7), with an IC50 of 31 nM.

IC50 & Target

IC50: 31 nM (Nav1.7)[1].

Clinical Trial
Molecular Weight

436.91

Formula

C19H21ClN4O4S

CAS No.
SMILES

O=C(C1=CC2=C(N(C3=CC(Cl)=C(OCC(C)C)N=C3)N=C2C)C=C1)NS(=O)(C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (228.88 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2888 mL 11.4440 mL 22.8880 mL
5 mM 0.4578 mL 2.2888 mL 4.5776 mL
10 mM 0.2289 mL 1.1444 mL 2.2888 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
PF-05241328
Cat. No.:
HY-103623
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