2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Nombre del producto No. CAS Pureza Estructura química
  • HY-N5203
    Ala0-Actagardine 223465-14-3 98%
    Ala0-Actagardine is a lantibiotic found in the cultures of Actinoplanes liguriae ATCC 31048.
    Ala0-Actagardine
  • HY-N5204
    Clavalanine 74758-63-7 98%
    Clavalanine (Ro 22-5417) inhibits a variety of bacteria and fungi.
    Clavalanine
  • HY-N6048
    Lancifodilactone F 850878-47-6 98%
    Lancifodilactone F (compound 1) can be isolated from the leaves and stems of Schisandra lancifolia. Lancifodilactone F has anti-HIV activity with EC50=20.69 μg/mL. Lancifodilactone F has cytotoxicity against C8166 cells (CC50 >200 μg/mL).
    Lancifodilactone F
  • HY-N6926
    1,3,5-Tricaffeoylquinic acid 1073897-80-9 98%
    1,3,5-Tricaffeoylquinic acid acts as an angiogenesis inhibitor and apoptosis inducer, and exhibits anti-HIV activity. 1,3,5-Tricaffeoylquinic acid inhibits the phosphorylation of VEGFR2, ERK, PI3K, Akt and mTOR in the angiogenesis signaling pathway. 1,3,5-Tricaffeoylquinic acid regulates apoptosis-related proteins, upregulates the levels of activated caspase-8, Bax, activated PARP and caspase-3/9, while downregulates the level of Bcl-2. 1,3,5-Tricaffeoylquinic acid inhibits tube formation and shows cytotoxicity against ovarian cancer cells. 1,3,5-Tricaffeoylquinic acid can be used in studies related to ovarian cancer.
    1,3,5-Tricaffeoylquinic acid
  • HY-N6936
    Sennidin A 641-12-3 98%
    Sennidin A, isolated from the leaves of Cassia angustifolia, inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation.
    Sennidin A
  • HY-N6994
    Isoasatone A 67451-73-4 99.86%
    Isoasatone A is a natural product isolated from the plant Heterotropa takaoi M., with anti-insect activity. Isoasatone A againsts S. litura by acting on cytochrome P450 monoxygenases and glutathione transferases.
    Isoasatone A
  • HY-N7165
    3-O-cis-p-Coumaroyl maslinic acid 69297-40-1 98%
    3-O-cis-p-Coumaroyl maslinic acid (compound 16) is a natural compound isolated from the ethyl acetate extract of leaves of Miconia albicans.3-O-cis-p-Coumaroyl maslinic acid can inhibit PTP1B, with the IC50 of 0.46 μM, and shows antimicrobial activity on Gram-positive bacteria and yeasts.
    3-O-cis-p-Coumaroyl maslinic acid
  • HY-N7188
    CJ-21,058 405072-57-3 98%
    CJ-21,058 is a potent SecA inhibitor with an IC50 value of 15 µg/mL. CJ-21,058 inhibits ATP-dependent translocation of precursor proteins across a bacterial cell membrane. CJ-21,058 shows antibacterial activity against Gram-positive bacteria.
    CJ-21,058
  • HY-N7236
    Pervicoside B 96157-95-8 98%
    Pervicoside B is a glycoside C isolated from Neothyone gibbosa sea cucumber. In vitro studies have shown that Pervicoside B has a potent antiparasitic effect against Leishmania mexicana, inhibiting 100% of promastigotes at 5-10 μg/mL. Pervicoside B also exhibits strong antifungal activity against Aspergillus niger, with MIC values ranging from 4.65 to 16.7 μg/mL. Pervicoside B has potential applications in the inhibition of parasitic infections and fungal diseases.
    Pervicoside B
  • HY-N7237
    Stichloroside B1 78244-74-3 98%
    Stichloroside B1 is a class of antifungal triterpenoid oligosaccharide isolated from the sea cucumber Stichopus chloronotus (BRANDT).
    Stichloroside B1
  • HY-N7242
    Plicacetin 43043-15-8 98%
    Plicacetin is a crystalline antibiotic isolated from the fermentation broth of Streptomyces actinomycetes and is structurally similar to Amicetin (HY-120383) and Bamicetin..
    Plicacetin
  • HY-N7322
    Swietemahalactone 1514669-21-6 98%
    Swietemahalactone is a natural compound isolated from Swietenia mahagoni. Swietemahalactone exhibits antibacterial activity aganist E. coli.
    Swietemahalactone
  • HY-N7374
    Cyperin 33716-82-4 98%
    Cyperine is a phytotoxic fungal metabolite that has been found in A. cypericola. It inhibits A. thaliana enoyl-acyl carrier protein reductase (ENR; IC50=89 μM). Cyperine induces necrosis in a panel of nine plant species in a leaf bioassay and inhibits root growth in A. thaliana seedlings (IC50=38.4 μM).
    Cyperin
  • HY-N7423
    Methyl isoferulate 16980-82-8 98%
    Methyl isoferulate (Isoferulic acid methyl ester) is an anti-H1N1 swine flu compound. Methyl isoferulate exerts its anti-swine flu activity by blocking the influenza M2 proton channel.
    Methyl isoferulate
  • HY-N7538
    Dealanylalahopcin 96565-32-1 98%
    Dealanylalahopcin is an antimicrobial agent that can be isolated from the culture filtrate of Streptomyces leucoderma subsp. ochraceus. Dealanylalahopcin can also be synthesized by enzymatic hydrolysis of alahopcin by microbial α-amino acid ester hydrolases. Dealanylalahopcin has weak antimicrobial activity against Gram-positive and Gram-negative bacteria and exhibits moderate inhibition of collagen prolyl hydroxylase.
    Dealanylalahopcin
  • HY-N7648
    Atherosperminine 5531-98-6 98%
    Atherosperminine (Atherospermine) is a phosphodiesterase inhibitor. Atherosperminine inhibits growth of chloroquine-resistant Plasmodium falciparum. Atherosperminine scavenges DPPH free radicals, exhibits ferric reducing power, and chelates metal ions. Atherosperminine can be used for the research of malaria.
    Atherosperminine
  • HY-N7747
    Sceptrin dihydrochloride 79703-25-6 98%
    Sceptrin dihydrochloride is a compound isolated from the sea sponge Agelas sceptrum that is an antimicrobial agent.
    Sceptrin dihydrochloride
  • HY-N7784
    Liriodenine methiodide 55974-07-7 98%
    Liriodenine methiodide is an antibiotic that is active against C. albicans and S. cereuisiae with antimicrobial activities.
    Liriodenine methiodide
  • HY-N7851
    Terpineol 8000-41-7
    Terpineol is a monoterpenoid alcohol compound that is widely found in plants, especially in the peels of citrus fruits. Terpineol has antioxidant, anti-inflammatory and antibacterial activities and is commonly used in the fragrance industry as an additive in food, beverages, cosmetics and perfumes.
    Terpineol
  • HY-N7854
    Anacardic acid diene 103904-74-1 98%
    Anacardic acid diene is a polyunsaturated form of anacardic acid (HY-N2020) that has been found in cashew nut shell liquid. It has antibacterial activity against methicillin resistant S. aureus (MRSA) and S. mutans (MICs=12.5 and 6.25 μg/mL, respectively). Anacardic acid diene has schistosomicidal activity against adult S. mansoni worms when used at a concentration of 100 μM. It also inhibits soybean lipoxygenase-1 in a time-dependent manner.
    Anacardic acid diene
Cat. No. Nombre del producto / Synonyms Application Reactivity