Metabolic Disease

CTPαS (Sp isomer) is a monomeric raw material that can be used for nucleic acid synthesis.

DMTr-S-5-C-Me-2'-O-Me-rU-3'-CE-phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.

Docosapentaenoylcarnitine (C22:5n3) is an endogenous metabolite of T3D-959.

Ligupurpuroside A is an active product that can be extracted from Ligustrum robustum. Ligupurpuroside A acts as a natural inhibitor of lipase in a competitive manner.

Methyl 3-hydroxyheptadecanoate is an ester product.

L-Palmitoylcarnitine-d₉ is deuterium labeled L-Palmitoylcarnitine. L-Palmitoylcarnitine, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine inhibits K_ATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2.

Cholesteryl 11(E)-vaccenate (Vaccenic acid cholesteryl ester) is an ester product.

(S,9E,11Z,14Z)-8-Hydroxyicosa-9,11,14-trienoic acid is an ester product.

DMTr-2'-O-Me-rG(iBu)-3'-(D)-DPSE-phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.

Anti-Monkey/Human CD20 Antibody (2H7) is a mouse-derived IgG2b κ type antibody inhibitor, targeting to monkey/human CD20. Anti-Monkey/Human CD20 Antibody (2H7) specifically depletes B cells. Anti-Monkey/Human CD20 Antibody (2H7) can be used for the researches of inflammation and metabolic disease, such as diabetes and experimental autoimmune encephalomyelitis.

Acetyl-L-carnitine-d6 (hydrochloride) is a deuterated Acetyl-L-carnitine. Acetyl-L-carnitine is an orally active mitochondrial energy metabolism regulator and neuroprotectant that can penetrate the blood-brain barrier.

GW0742 (Standard) is the analytical standard of GW0742. This product is intended for research and analytical applications. GW0742 is a potent PPARβ and PPARδ agonist, with an IC50 of 1 nM for human PPARδ in binding assay, and EC50s of 1 nM, 1.1 μM and 2 μM for human PPARδ, PPARα, and PPARγ, respectively.

trans-Cyclohexane-1,2-diol (Standard) is the analytical standard of trans-Cyclohexane-1,2-diol (HY-W010514). This product is intended for research and analytical applications. trans-Cyclohexane-1,2-diol (TCHD) is a transient dilator of the nuclear pore complex (NPC). By interacting with the hydrophobic core (FG nucleoporin) of the NPC, trans-Cyclohexane-1,2-diol can disrupt the NPC structure and reversibly increase the permeability of the nuclear pore, allowing macromolecules larger than 40 kDa (such as plasmid DNA) to enter the cell nucleus by passive diffusion, thereby enhancing the nuclear import efficiency of non-viral vectors. trans-Cyclohexane-1,2-diol can improve the efficiency of in vitro electrotransfection or lipid-mediated gene transfection, especially significantly increasing gene expression in differentiated airway epithelial cells.

Phytanic acid ethyl ester is an ester product.

L-erythro-Dihydrosphingosine is an ester product.

1-Linoleoyl-3-chloropropanediol (Rac-1-Linoleoyl-3-chloropropanediol) is a lipid product.

MCPD dioleate (1,2-Dioleoyl-3-chloropropanediol) is an ester product.

Pyridindolol (NSC 266530) is a β-galactosidase inhibitor. Pyridindolol can be produced by actinomycetes.

SB 415286 (Standard) is the analytical standard of SB 415286. This product is intended for research and analytical applications. SB 415286 is a potent and selective cell permeable inhibitor of GSK-3α, with an IC50 of 77.5 nM, and a Ki of 30.75 nM; SB 415286 is equally effective at inhibiting human GSK-3α and GSK-3β.

N-Octadecanoyl-sulfatide is an ester product.