1. Terpenoids and Glycosides
  2. Ryanodine

Ryanodine 

Cat. No.: HY-103306 Purity: >99.0%
Handling Instructions

Ryanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa.

For research use only. We do not sell to patients.

Ryanodine Chemical Structure

Ryanodine Chemical Structure

CAS No. : 15662-33-6

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Description

Ryanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa.

IC50 & Target

Ryanodine receptor[1]

In Vivo

Ryanodine (100-5000 nM, 30-120 mintutes) irreversibly depresses twitch and tetanic tension of both fast and slow muscle in a dose-related manner[1].

At concentrations above 250 nM, ryanodine induces a slowly developing, dose dependent contracture which could not be blocked by 5 mMCo2+[1].

Clinical Trial
Molecular Weight

493.55

Formula

C₂₅H₃₅NO₉

CAS No.

15662-33-6

SMILES
Shipping

Room temperature in continental US; may vary elsewhere

Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
References

Purity: >99.0%

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Ryanodine
Cat. No.:
HY-103306
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