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Cat. No.: HY-U00184

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Timepidium bromide

Name: Timepidium bromide
Brand: MedChemExpress
SKU: HY-U00184
Availability: PreOrder

(Synonyms: Sesden; SA504)

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Timepidium bromide (Sesden; SA504) is an anticholinergic agent.

For research use only. We do not sell to patients.

CAS No.: 35035-05-3
Formula: C₁₇H₂₂BrNOS₂
Molecular Weight:400.40

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Timepidium bromide Chemical Structure

CAS No.: 35035-05-3

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- In Vivo
Chemical Information
Publications (1)
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Biological Activity

Description

Timepidium bromide (Sesden; SA504) is an anticholinergic agent.

IC₅₀ & Target

Cholinergic^[1]

All mAChR Isoforms :

In Vivo

Effects of Timepidium bromide (TB), acetylcholine (ACh) and neostigmine (Neost) on gastric and duodenal blood flow distribution are studied by the use of ¹³¹I-labeled macroaggregated human serum albumin (MAA) in rabbits. In normal rabbits, gastric blood flow is found to be uneven in various regions of the stomach: anterior corpus (50% of total gastric blood flow) greater than posterior corpus (40%) greater than pyloric antrum (7%). Intravenous administration of Timepidium bromide (200 μg/kg) to normal rabbits produces a slight increase in total gastric blood flow, but the increase in the mucosal layer of the pyloric antrum is considerable^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 35035-05-3
Molecular Weight 400.40
Formula C₁₇H₂₂BrNOS₂
SMILES

C[N+]1(C)C/C(CC(OC)C1)=C(C2=CC=CS2)\C3=CC=CS3.[Br-]
Synonyms

Sesden; SA504
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Research Square Preprint

2021 Aug.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Naito K, et al. Effect of timepidium bromide, an anticholinergic agent, on gastric and duodenal blood flow distribution in rabbits. Jpn J Pharmacol. 1982 Feb;32(1):73-80. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

Timepidium bromide

1 Cited Publications

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Biological Activity
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- In Vivo
Chemical Information
Publications (1)
Purity & Documentation
References

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Timepidium bromide

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All mAChR Isoforms