1. PROTAC
  2. Ligand for E3 Ligase

TNF-α-IN-1 

Cat. No.: HY-112275
Handling Instructions

TNF-α-IN-1 is a TNF-α inhibitor extracted from patent US20030096841A1, compound example I-7.

For research use only. We do not sell to patients.

TNF-α-IN-1 Chemical Structure

TNF-α-IN-1 Chemical Structure

CAS No. : 444287-49-4

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

TNF-α-IN-1 is a TNF-α inhibitor extracted from patent US20030096841A1, compound example I-7.

IC50 & Target

TNF-α[1]

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7491 mL 13.7457 mL 27.4914 mL
5 mM 0.5498 mL 2.7491 mL 5.4983 mL
10 mM 0.2749 mL 1.3746 mL 2.7491 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

363.75

Formula

C₁₆H₁₄ClN₃O₅

CAS No.

444287-49-4

SMILES

O=C(NCC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CCl

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
TNF-α-IN-1
Cat. No.:
HY-112275
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TNF-α-IN-1

Cat. No.: HY-112275