2. Signaling Pathways
  3. GPCR/G Protein
    Immunology/Inflammation
  4. CCR
  5. CCR Ligand

CCR Ligand

CCR Isoform Comparison

CCR Ligands (3):

Cat. No. Product Name Effect Purity
  • HY-P991541
    HGS101
    		Ligand
    HGS101 is a fully human CCR5 monoclonal antibody with high affinity to CCR5. HGS101 binds to the 2nd extracellular loop (ECL-2) and acts as a signal antagonist. HGS101 restores Maraviroc (HY-13004) inhibition of Maraviroc-resistant HIV-1 infection of PBMCs. HGS101 shows anti-HIV activity by inhibiting CCR5 signaling in simian immunodeficiency virus-uninfected RMs models.
  • HY-181288
    CCR9 ligand-Linker Conjugate 1
    		Ligand
    CCR9 ligand-Linker Conjugate 1 is a target protein ligand-linker conjugate containing a CCR9 ligand and a PROTAC linker, which recruits E3 ligases. USP7 Ligand-Linker Conjugates 1 can be used to synthesize PROTAC CCR9 Degrader 1 (HY-181287).
  • HY-180572
    CCR2 ligand-1
    		Ligand
    CCR2 ligand-1 is a ligand for CCR2. CCR2 ligand-1 conjugates with the Linker PIN1 degrader-3 (HY-79577) and the E3 ligase ligand Thalidomide 4-fluoride (HY-41547) can be used for the synthesis of LUF7996 (HY-180571).