Acyltransferase
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Acyltransferase Related Products (202)
Related Products (202)
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Phenylpyropene A
0 ImagesCat. No.: HY-N10234CAS No.: 189564-20-3Phenylpyropene A, a fungal metabolite, is a potent acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor with an IC50 of 0.8 μM.
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Eldacimibe
0 ImagesCat. No.: HY-106938CAS No.: 141993-70-6Synonyms: WAY-ACA 147Eldacimibe is an ACAT2 inhibitor. Eldacimibe can lower plasma cholesterol levels by blocking cholesterol absorption and can prevent macrophages from turning into foam cells. Eldacimibe can be used in the study of cardiovascular diseases (atherosclerosis), endocrine and metabolic diseases (hypercholesterolemia) .
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CL 277082
0 ImagesCat. No.: HY-129344CAS No.: 96224-26-9CL 277082 is a potent and selective acyl CoA:cholesterol acyltransferase (ACAT) inhibitor in microsomes. CL 277082 inhibits ACAT with IC50 values of 0.14 μM for intestinal mucosal microsomes, 0.74 μM for liver, and 1.18 μM for rat adrenal. CL 277082 is a ACAT-catalyzed cholesterol esterification and cholesterol absorption inhibitor.
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Obeversen sodium scrambled negative control
0 ImagesCat. No.: HY-145624BObeversen sodium scrambled negative control is the sequence scrambled negative control of Obeversen sodium.
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Pradigastat sodium
0 ImagesCat. No.: HY-16278ACAS No.: 956136-98-4Synonyms: LCQ 908 sodiumPradigastat sodium (LCQ 908 sodium) is a selective and orally effective diacylglyceryl acyltransferase 1 (DGAT1) inhibitor with IC50 at 0.157 µM. Pradigastat is primarily used to study diseases associated with abnormal triglyceride metabolism. Pradigastat has anti-obesity and anti-diabetic effects. Pradigastat inhibited BCRP, OATP1B1, OATP1B3 and OAT3 activities with IC50 of 5 µM, 1.66µM, 3.34µM and 0.973µM, respectively. In addition, Pradigastat has antiviral activity and can inhibit hepatitis C virus replication in vitro.
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Obeversen
0 ImagesCat. No.: HY-145624CAS No.: 2304711-30-4Synonyms: ION-769357Obeversen is an antisense oligonucleotide that inhibits the synthesis of diacylglycerol acyltransferase 2 (DGAT-2). Obeversen can be used in the research of nonalcoholic fatty liver disease.
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ACAT-IN-10
0 ImagesCat. No.: HY-139027CAS No.: 454203-40-8ACAT-IN-10 is an acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor extracted from patent EP1236468A1, example 197. ACAT-IN-10 weakly inhibits NF-κB mediated transcription.
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MGAT2-IN-4
0 ImagesCat. No.: HY-149893CAS No.: 1841424-92-7
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FR-190809
0 ImagesCat. No.: HY-122078CAS No.: 215589-63-2FR-190809 is a potent, nonadrenotoxic, orally efficacious acyl-CoA:cholesterol O-acyltransferase (ACAT) inhibitor, with an IC50 of 45 nM.
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Diacylglycerol acyltransferase inhibitor-2
0 ImagesCat. No.: HY-162854CAS No.: 2186700-48-9Diacylglycerol acyltransferase inhibitor-2 (Example 8) is an inhibitor of Diacylglycerol Acyl Transferase 2 (DGAT2) with an IC50 value of 3.7 nM.
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10-Deacetylbaccatin III 10-O-acetyltransferase
0 ImagesCat. No.: HY-E7117310-Deacetylbaccatin III 10-O-acetyltransferase (EC 2.3.1.167) belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups.
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Obeversen sodium
0 ImagesCat. No.: HY-145624ACAS No.: 2304711-35-9Synonyms: ION-769357 sodiumObeversen sodium is an antisense oligonucleotide that inhibits the synthesis of Diacylglycerol acyltransferase 2 (DGAT-2). Obeversen sodium can be used in the research of nonalcoholic fatty liver disease.
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ACAT-IN-4 hydrochloride
0 ImagesCat. No.: HY-139021ACAS No.: 199984-46-8ACAT-IN-4 hydrochloride (Example 208) is an acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor. ACAT-IN-4 hydrochloride inhibits NF-κB mediated transcription.
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Oleyl anilide
0 ImagesOleyl anilide (Oleic acid anilide) is a toxic agent found in some stocks of toxic oil, which is associated with toxic oil syndrome (TOS). Oleyl anilide is an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT) (IC50: 26 µM).
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9''-Methyl lithospermic acid
0 ImagesCat. No.: HY-N20677CAS No.: 1151683-53-29''-Methyl lithospermic acid is a serine palmitoyltransferase (SPT) activator. 9''-Methyl lithospermic acid increases the levels of SPT1 and SPT2 in human keratinocytes. 9''-Methyl lithospermic acid maintains epidermal permeability barrier function by promoting SPT expression.
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Ilexoside XLVIII
0 ImagesCat. No.: HY-N9524CAS No.: 129095-76-7
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Amidepsine D
0 ImagesCat. No.: HY-129295CAS No.: 79786-34-8Amidepsine D is a fungal metabolite isolated from the culture broth of Humicola sp. FO-2942 that inhibits Diacylglycerol acyltransferases (DGAT) activity.
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Lecimibide
0 ImagesCat. No.: HY-16281CAS No.: 130804-35-2Synonyms: DuP 128Lecimibide (DuP 128) is a potent and specific acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor for antihyperlipidemia research.
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F-1394
0 ImagesCat. No.: HY-106902CAS No.: 162490-89-3F-1394 is an orally active acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor that inhibits dietary cholesterol absorption in mice. F-1394 can be used in cardiovascular disease research.
