Drug Metabolite
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
All Product Categories
-
Drug Metabolite Related Products (1984)
Related Products (1984)
-
Antibodies (1)
-
Related Compound Screening Libraries (1)
-
Nafimidone alcohol
0 ImagesCat. No.: HY-129718CAS No.: 71009-17-1Nafimidone alcohol is the major metabolic of Nafimidone in plasma and urine. Nafimidone alcohol is promising for research of onset seizures.
-
a-Hydroxymetoprolol (Standard)
0 ImagesCat. No.: HY-134670RCAS No.: 56392-16-6a-Hydroxymetoprolol (Standard) is the analytical standard of a-Hydroxymetoprolol. This product is intended for research and analytical applications. a-Hydroxymetoprolol is a metabolite of metoprolol. The adrenoreceptor blocking effect of a-Hydroxymetoprolol on metoprolol is almost zero.
-
G-25671
0 ImagesCat. No.: HY-W551882CAS No.: 3736-92-3G-25671 is a platelet cyclooxygenase (COX) inhibitor (Ki = 4.5 μM) and uricosuric agent, as well as the active metabolite of Sulfinpyrazone (HY-B1271). G-25671 reduces the production of thromboxane B2 and malondialdehyde from arachidonic acid (AA), and inhibits human platelet aggregation induced by Sodium arachidonate (HY-109590A). G-25671 can be used in gout-related research.
-
PNU 142300
0 ImagesCat. No.: HY-125074CAS No.: 368891-69-4
-
4,5-Desisopropylidene topiramate
0 ImagesCat. No.: HY-W700165CAS No.: 106881-41-84,5-Desisopropylidene topiramate is the major metabolite of Topiramate (HY-B0122).
-
13(S)-HOTrE
0 Images13 (S)-HOTrE is an oxylipin metabolite of α-Linolenic acid (HY-N0728). 13 (S)-HOTrE mediates the inactivation of the NLRP3 inflammasome through the PPAR-γ pathway to exert anti-inflammatory effects. 13 (S)-HOTrE inhibits NF-κB nuclear translocation, ROS production, autophagy and IL-1β levels, induces apoptosis, and increases IL-10 levels. 13 (S)-HOTrE alleviates LPS-induced inflammatory responses in macrophages, prolongs the survival time of septic mice, and regulates the immunometabolic phenotype in parenteral nutrition mouse models. 13 (S)-HOTrE can be used in the research of immune and inflammation-related diseases.
-
2',2'-Difluorodeoxyuridine 5'-monophosphate
0 ImagesCat. No.: HY-185841CAS No.: 139729-89-8Synonyms: dFdUMP2',2'-Difluorodeoxyuridine 5'-monophosphate (dFdUMP) is a metabolite of Gemcitabine (HY-17026) and an inhibitor of Thymidylate synthase, with an inhibition constant of 130 μM. 2',2'-Difluorodeoxyuridine 5'-monophosphate can be used in research related to ovarian cancer, hematologic malignancies, non-small cell lung cancer, pancreatic cancer, soft tissue sarcoma, and glioblastoma multiforme.
-
Ramiprilat-d4 hydrochloride
0 ImagesCat. No.: HY-A0115S2Synonyms: Ramiprilat-d4 hydrochlorideRamiprilat-d4 hydrochloride is deuterated labeled Ramiprilat (HY-A0115). Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research.
-
6-Hydroxybenzbromarone (Standard)
0 ImagesCat. No.: HY-135774RCAS No.: 152831-00-01-(Carboxymethyl)cyclohexanecarboxylic acid (Standard) is the analytical standard of 1-(Carboxymethyl)cyclohexanecarboxylic acid. This product is intended for research and analytical applications. 1-(Carboxymethyl)cyclohexanecarboxylic acid (1-Carboxycyclohexaneacetic acid; Gabapentin Impurity E) is a potential impurity in commercial preparations of the antiepileptic agent Gabapentin (HY-A0057). It is also used as a precursor for the synthesis of a serotonin (5-HT) receptor subtype 5-HT2A antagonist.
-
Monopropyl phthalate
0 ImagesCat. No.: HY-W703398CAS No.: 4376-19-6Monopropyl phthalate is a compound derived from the hydrolysis of Dipropyl phthalate (DPrP). Monopropyl phthalate is hydrolyzed to PA. DPrP shows significant dose-dependent toxic effects on K. brevis.
-
Pergolide sulfone
0 ImagesCat. No.: HY-137306CAS No.: 72822-03-8Pergolide sulfone is a Pergolide metabolite.
-
7-Hydroxy etodolac
0 ImagesCat. No.: HY-W725632CAS No.: 101901-07-9Synonyms: 7-OH-ET
-
(±)-p-Fluoro pseudoephedrine hydrochloride
0 ImagesCat. No.: HY-W743525CAS No.: 7799-73-7(±)-p-Fluoro pseudoephedrine hydrochloride is a metabolite of 4-Fluoromethdrug derivative.
-
Desmonomethylpromazine
0 ImagesCat. No.: HY-W641657CAS No.: 2095-20-7
-
5-HO-Ehdpp
0 ImagesCat. No.: HY-W722114CAS No.: 2173149-33-0Synonyms: 5-OH-EHDPP5-HO-Ehdpp (5-OH-EHDPP) is a flame retardant.
-
15-Hydroxy Lubiprostone
0 ImagesCat. No.: HY-164998CAS No.: 475992-30-4
-
Ampicilloic acid
0 ImagesCat. No.: HY-133841CAS No.: 32746-94-4Synonyms: Ampicillin impurity DAmpicilloic acid (Ampicillin impurity D) is a hydrolytic metabolite of the penicillin antibiotic Ampicillin (HY-B0522), produced by Alcanivorax sp. via β-lactamase-mediated β-lactam ring opening reaction.
-
N-Acetyl serotonin β-D-glucuronide
0 ImagesCat. No.: HY-W777236CAS No.: 18430-06-3
-
N-Acetyl lenalidomide
0 ImagesCat. No.: HY-W712534CAS No.: 1421593-80-7N-Acetyl lenalidomide is a metabolite of Lenalidomide (HY-A0003), which is formed by hydrolysis of Lenalidomide in plasma and urine.
