Drug Metabolite
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
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Drug Metabolite Related Products (2022)
Related Products (2022)
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Antibodies (1)
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Related Compound Screening Libraries (1)
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Cholic acid 3-sulfate
0 ImagesCat. No.: HY-N17272CAS No.: 66167-89-3Cholic acid 3-sulfate is the sulfated metabolite of Cholic acid (HY-N0324), produced by liver enzyme sulfotransferase-2A1. Cholic acid 3-sulfate is less toxic than the parent compound, thus serving as a detoxification pathway for bile acids. Cholic acid 3-sulfate does not have the effect of stimulating intestinal secretion.
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2-Formyl sunitinib
0 ImagesCat. No.: HY-W754546CAS No.: 2377533-92-9
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Alpelisib carboxylic acid
0 ImagesCat. No.: HY-W728123CAS No.: 2715981-74-9
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Antitumor agent-207
0 ImagesCat. No.: HY-178962Antitumor agent-207 (compound 10K) is a Pt(IV)-NO prodrug with high lipid solubility, good stability, and excellent tumor targeted release ability. Antitumor agent-207 has significant anti proliferative activity in various cells such as TE-1 (IC50 = 1.79 μM), TE-10 (IC50 = 1.95 μM), KYSE-30 IC50 = 5.99 μM), KYSE-520 (IC50 = 5.53 μM) cells. Antitumor agent-207 can significantly enhance intracellular Pt accumulation and DNA platformization levels, and effectively release NO. Antitumor agent-207 can be used for research on cancers such as esophageal cancer.
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Norzotepine
0 ImagesCat. No.: HY-187004CAS No.: 78846-91-0Norzotepine is the major human metabolite of Zotepine (HY-103093) and also a NET inhibitor (human IC50 = 4.2 nM). Norzotepine exerts antipsychotic-like and antidepressant-like effects by inhibiting Norepinephrine (HY-13715) reuptake and blocking dopamine D2 (Dopamine D2), histamine H1 (Histamine H1), and 5-HT2 receptors. Norzotepine can be used for research on schizophrenia.
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Etherolenic acid
0 ImagesCat. No.: HY-158547CAS No.: 169217-39-4Etherolenic acid, a divinyl ether oxylipin, is a metabolite of Linolenic acid.
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MDL 72392
0 ImagesCat. No.: HY-182727CAS No.: 85278-68-8MDL 72392 is a selective irreversible monoamine oxidase A (MAO-A) inhibitor. MDL 72392 inhibits MAO-A. MDL 72392 is formed by decarboxylation of the bioprecursor amino acid MDL 72394 via aromatic L-amino acid decarboxylase. MDL 72392 can be used in melatonin biosynthesis research.
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Quetiapine Sulfoxide-d8
0 ImagesCat. No.: HY-G0014SCAS No.: 1330238-38-4Quetiapine Sulfoxide-d8 is the deuterium labeled Quetiapine sulfoxide. Quetiapine sulfoxide (Quetiapine S-oxide) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist.
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L-731120
0 ImagesCat. No.: HY-178088CAS No.: 2232226-16-1L-731120 is an alkyl citrate zargozaga acid A analogue, which is secondary metabolite produced by fungal fermentation. L-731120 shows inhibitory activity against squalene synthase (SQS) (IC50 = 260 nM). L-731120 can inhibit the synthesis of cholesterol in the liver. L-731120 can be used for the research of infection and metabolic disease, such as hypercholesterolemia.
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N-Demethylerythromycin A
0 ImagesN-Demethylerythromycin A is a metabolite of Erythromycin A. Erythromycin A is an antibiotic.
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8-Aminoclonazolam
0 ImagesCat. No.: HY-137152CAS No.: 71368-66-68-Aminoclonazolam is a benzodiazepine and clonazolam metabolite.
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(R)-6-Hydroxybuspirone
0 ImagesCat. No.: HY-116627CAS No.: 477930-30-6Synonyms: BMS-442608
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Milsaperidone
0 ImagesCat. No.: HY-G0003ACAS No.: 501373-88-2Synonyms: (S)-Hydroxy Iloperidone; VHX-896Milsaperidone ((S)-Hydroxy Iloperidone; VHX-896) is an orally active serotonin 5-HT2A and dopamine D2 receptor antagonist. Milsaperidone ((S)-Hydroxy Iloperidone) is the active metabolite of the antipsychotic agent Iloperidone (HY-17410). Milsaperidone can be used in studies related to mental disorders such as depression.
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N-Desmethyl zopiclone-d8
0 ImagesCat. No.: HY-U00199SCAS No.: 1189805-43-3N-Desmethyl zopiclone-d8 is deuterium labeled Norzopiclone. Norzopiclone is the inactive metabolite of Zopiclone. Norzopiclone has some anxiolytic properties.
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Glycidamide-13C3
0 ImagesCat. No.: HY-W776973CAS No.: 1216449-31-8Synonyms: Oxiranecarboxamide-13C3; 2,3-Epoxypropanamide-13C3Glycidamide-13C3 (Oxiranecarboxamide-13C3) is the 13C-labeled Glycidamide (HY-119329). Glycidamide is the genotoxic metabolite of Acrylamide. Glycidamide can react with proteins, such as hemoglobin, or with DNA, and induces genotoxic effects.
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Idoxanthin
0 ImagesCat. No.: HY-W750708CAS No.: 25510-19-4Idoxanthin is a metabolite of Astaxanthin (HY-B2163). Idoxanthin is involved in the metabolic pathway of Carotenoids, and its formation and accumulation reflect the metabolic capacity and metabolic pathways of different fish species.
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6-T-5'-GMP disodium
0 ImagesCat. No.: HY-134242CAS No.: 74686-78-5Synonyms: 6-Thioguanosine monophosphate disodium; 6-Thio-GMP disodium6-T-5'-GMP disodium is an analogue of guanosine-5'-O-monophosphate (5'-GMP) and a metabolite of an immunosuppressive drug, azathioprine (HY-B0256).
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ZM 213689
0 ImagesCat. No.: HY-164611CAS No.: 124190-28-9
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Abiraterone N-oxide-d4
0 ImagesCat. No.: HY-144957SAbiraterone N-oxide-d4 is the deuterium labeled Abiraterone N-oxide (HY-148376). Abiraterone N-oxide is a metabolite of Abiraterone (HY-148377). Abiraterone is a potent and irreversible?CYP17A1 inhibitor?with antiandrogen activity.
