Drug Metabolite
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
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Drug Metabolite Related Products (2022)
Related Products (2022)
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Antibodies (1)
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Related Compound Screening Libraries (1)
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Threo-dihydrobupropion-d9 hydrochloride
0 ImagesCat. No.: HY-W738587CAS No.: 2747918-83-6rac-threo-Dihydro Bupropion Hydrochloride-d9 is the deuterium labeled Threo-dihydrobupropion hydrochloride (HY-131479). Threo-dihydrobupropion hydrochloride is a primary metabolite of Bupropion. Threo-dihydrobupropion hydrochloride can be used for the research of the depression, behavioral, and biochemistry.
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Masoprocol tetrapivalate
0 ImagesCat. No.: HY-182264CAS No.: 180634-64-4Synonyms: Nordihydroguaiaretic acid tetrapivalateMasoprocol tetrapivalate (Nordihydroguaiaretic acid tetrapivalate) is a catecholic butane metabolite and also a tyrosine kinase activity inhibitor of IGF-1R and EGFR. Masoprocol tetrapivalate regulates tyrosine kinase signaling pathways associated with cell proliferation. Masoprocol tetrapivalate can be used in the research of proliferative diseases, including malignant, precancerous or benign cancers, and solid tumors.
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cyclo-Cannabigerol
0 ImagesCat. No.: HY-172540Synonyms: cyclo-CBGcyclo-Cannabigerol (cyclo-CBG) is the major metabolite of Cannabigerol generated by cytochrome P450. Cyclo-Cannabigerol has weak anti-inflammatory activity.
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Aszonalenin
0 ImagesCat. No.: HY-123006CAS No.: 81797-27-5Aszonalenin is a metabolite of Aspergillus zonatus.
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Chondroitin disaccharide Δdi-0S sodium
0 ImagesCat. No.: HY-137208CAS No.: 136132-69-9Chondroitin disaccharide Δdi-0S sodium is an unsaturated disaccharide produced by the degradation of Chondroitin sulfate (HY-B2162). Chondroitin disaccharide Δdi-0S sodium produces fluorescent pyridylamino derivative with 2-aminopyridine, which can be used in studies about the metabolic pathway of Chondroitin sulfate and related disease mechanisms.
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2-(Benzhydrylsulfinyl)acetic acid-d10
0 ImagesCat. No.: HY-W701262CAS No.: 1246819-82-8Synonyms: Modafinil acid-d102-(Benzhydrylsulfinyl)acetic acid-d10 (Modafinil acid-d10) is the deuterium labeled 2-(Benzhydrylsulfinyl)acetic acid (HY-W103882). 2-Benzhydrylsulfinylacetic acid (Modafinil acid) is the metabolite of modafinil.
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N-Deschlorobenzoyl indomethacin-d3
0 ImagesCat. No.: HY-W706737CAS No.: 3029090-15-8N-Deschlorobenzoyl indomethacin-d3 is the deuterium labeled N-Deschlorobenzoyl indomethacin (HY-W008567). N-Deschlorobenzoyl indomethacin (Compound 18), the primary metabolite of indomethacin (HY-14397), lacks the N-p-chlorobenzoyl group in its structure. Consequently, N-Deschlorobenzoyl indomethacin loses inhibitory activity against AKR1C2 and AKR1C3 (AKR1C2 IC50 =100 μM, AKR1C3 IC50 >100 μM), exhibiting no selectivity.
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α-Hydroxytamoxifen
0 ImagesCat. No.: HY-118517CAS No.: 97151-02-5Synonyms: (E)-α-Hydroxy tamoxifen; α-OHTAMα-Hydroxytamoxifen is a metabolite of tamoxifen, reacts with DNA in the absence of metabolizing enzymes, and causes formation of DNA adducts.
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4-Epioxytetracycline (Standard)
0 ImagesCat. No.: HY-125947RCAS No.: 14206-58-74-Epioxytetracycline (Standard) is the analytical standard of 4-Epioxytetracycline. This product is intended for research and analytical applications. 4-Epioxytetracycline, the degradation product of Oxytetracycline (OTC), can be found in swine manure compost and wastewater.
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7-Hydroxy coumarin glucuronide sodium-13C6
0 ImagesCat. No.: HY-W7663327-Hydroxy coumarin glucuronide sodium-13C6 is the 13C-labeled 7-Hydroxy coumarin glucuronide sodium (HY-120201). 7-Hydroxy coumarin glucuronide sodium is a benzopyrone and a metabolite of 7-hydroxy coumarin.
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2-Deoxokanshone L
0 ImagesCat. No.: HY-N12842CAS No.: 1884590-18-42-Deoxokanshone L is a degradation product of Nardosinone (HY-N0380).
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N1-Acetyl-5-methoxykynuramine hydrochloride
0 ImagesCat. No.: HY-W587743CAS No.: 1215711-91-3Synonyms: AMK hydrochlorideN1-Acetyl-5-methoxykynuramine hydrochloride (AMK hydrochloride) is an active metabolite of Melatonin (HY-B0075) with antioxidant activity and blood-brain barrier permeability. N1-Acetyl-5-methoxykynuramine hydrochloride inhibits LPS-induced activation of inducible nitric oxide synthase and COX-2, scavenges ROS, hydroxyl radicals, carbonate radicals and ABTS cation radicals, and protects bovine serum albumin from peroxyl radical-mediated damage. N1-Acetyl-5-methoxykynuramine hydrochloride reduces the increase in cytoplasmic and mitochondrial lipid peroxidation in the substantia nigra and striatum in MPTP (HY-15608)-induced mouse models of Parkinson's disease. N1-Acetyl-5-methoxykynuramine hydrochloride can be used in studies related to Parkinson's disease, metabolism-related diseases and oxidative stress.
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Megestrol-d3
0 ImagesCat. No.: HY-W747043CAS No.: 162462-71-7
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1H-1-Ethyl Candesartan Cilexetil
0 ImagesCat. No.: HY-135180CAS No.: 914613-35-71H-1-Ethyl Candesartan Cilexetil is a potential impurity found in bulk preparations of Candesartan Cilexetil (HY-17505).
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Desmethyl Bosentan
0 ImagesCat. No.: HY-145516CAS No.: 253688-61-8Synonyms: Ro 47-8634Desmethyl bosentan is an active metabolite of the endothelin receptor antagonist bosentan (HY-A0013).1 Desmethyl bosentan (25 μM) activates the pregnane X receptor (PXR) in CV-1 monkey kidney cells expressing the human receptor in a reporter assay.
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N-Didesmethyl Loperamide
0 ImagesCat. No.: HY-W700684CAS No.: 66164-06-5Synonyms: R 21345N-Didesmethyl Loperamide is a metabolite of Loperamide; a new and improved PET radiotracer for imaging P-gp function.
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Olmesartan ethyl ester
0 ImagesOlmesartan ethyl ester (compound 11) is an Olmesartan impurity. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist used to in the high blood pressure study.
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Ranitidine S-oxide (Standard)
0 ImagesCat. No.: HY-W011245RCAS No.: 73851-70-4Ranitidine S-oxide (Standard) is the analytical standard of Ranitidine S-oxide. This product is intended for research and analytical applications. Ranitidine S-oxide is the metabolite of Ranitidine (HY-B0693). Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion.
