HBV
Hepatitis B virus
HBV (Hepatitis B virus), abbreviated HBV, is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. HBV causes the disease hepatitis B. The hepatitis B virus is classified as the type species of the Orthohepadnavirus, which contains three other species: the Ground squirrel hepatitis virus, Woodchuck hepatitis virus, and theWoolly monkey hepatitis B virus. The genus is classified as part of the Hepadnaviridae family. HBV is divided into four major serotypes (adr, adw, ayr, ayw) based on antigenic epitopes present on its envelope proteins, and into eight genotypes (A–H) according to overall nucleotide sequence variation of the genome. The genotypes have a distinct geographical distribution and are used in tracing the evolution and transmission of the virus. Differences between genotypes affect the disease severity, course and likelihood of complications, and response to treatment and possibly vaccination.
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HBV Related Products (378)
Related Products (378)
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Antibodies (2)
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AB-161
0 ImagesCat. No.: HY-159987CAS No.: 2848560-66-5AB-161 is an orally active HBV RNA destabilizer and a PAPD5/7 inhibitor, with its primary action focused in the liver. AB-161 treats Hepatitis B Virus (HBV) infection by lowering the levels of Hepatitis B surface antigen (HBsAg), with an EC50 value of 2.2 nM for HBsAg. AB-161 can be used in the field of HBV infection research.
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LP10
0 ImagesCat. No.: HY-113648CAS No.: 1025400-45-6LP10 is a non-azole CYP51 inhibitor with activity against Trypanosoma cruzi infection. Treatment with LP10 blocks the 14α-demethylation step, leading to disruption of the parasite cell membrane and ultimately triggering the death of important clinically relevant amoeba stages.
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Metacavir
0 ImagesCat. No.: HY-116154CAS No.: 120503-45-9Metacavir is an orally active, potent and specific nucleoside reverse transcriptase inhibitor against hepatitis B virus (HBV) with antiviral activity.
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DVR-01
0 ImagesCat. No.: HY-122209CAS No.: 330461-34-2
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HBV Seq2 aa:28-39
0 ImagesCat. No.: HY-P4044CAS No.: 168417-72-9
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Lagociclovir valactate
0 ImagesCat. No.: HY-107026CAS No.: 1001670-19-4Lagociclovir valactate is a prodrug of Lagociclovir (HY-14844). Lagociclovir valactate is an orally active anti-HBV agent.
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Selgantolimod (Standard)
0 ImagesCat. No.: HY-109137RCAS No.: 2004677-13-6Synonyms: GS-9688 (Standard)Selgantolimod (Standard) is the analytical standard of Selgantolimod (HY-109137). This product is intended for research and analytical applications. Selgantolimod (GS-9688) is an orally active, potent and selective toll-like receptor 8 (TLR8) agonist for the treatment of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infection.
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Cyprosulfamide-d4
0 ImagesCat. No.: HY-W616313S
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(-)-Anicyphos
0 ImagesCat. No.: HY-W351380CAS No.: 98674-83-0(-)-Anicyphos is a chiral catalyst with the activity of promoting the selectivity of specific reactions. (-)-Anicyphos is often used to synthesize complex chiral molecules in organic synthesis and shows excellent catalytic performance. By adjusting the reaction conditions, (-)-Anicyphos can significantly improve the stereospecificity of the product, providing an effective strategy for compound development.
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Morphothiadin (Standard)
0 ImagesCat. No.: HY-108917RCAS No.: 1092970-12-1Synonyms: GLS4 (Standard)Morphothiadin (Standard) is the analytical standard of Morphothiadin (HY-108917). This product is intended for research and analytical applications. Morphothiadin is a potent inhibitor on the replication of both wild-type and adefovir (HY-B1826)-resistant HBV with an IC50 of 12 nM.
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KKJ00626
0 ImagesCat. No.: HY-W070093CAS No.: 51646-17-4
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Adefovir dipivoxil (Standard)
0 ImagesSynonyms: GS 0840 (Standard)Adefovir dipivoxil (Standard) is the analytical standard of Adefovir dipivoxil. This product is intended for research and analytical applications. Adefovir dipivoxil is an orally active adenosine analog and Adefovir prodrug. Adefovir dipivoxil inhibits DNA synthesis, activates the ATR signaling pathway, and disrupts the KCTD12-CDK1 interaction. Adefovir dipivoxil has antiviral activity against PRV, HBV, and orthopoxviruses. Adefovir dipivoxil has inhibitory effects on both lamivudine-resistant and wild-type strains. Adefovir dipivoxil has antitumor activity against lung and colon cancer.
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Entecavir monohydrate (Standard)
0 ImagesSynonyms: BMS200475 monohydrate (Standard); SQ34676 monohydrate (Standard)Entecavir (monohydrate) (Standard) is the analytical standard of Entecavir (monohydrate). This product is intended for research and analytical applications. Entecavir monohydrate (BMS200475 monohydrate; SQ34676 monohydrate) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell.
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Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside
0 ImagesCat. No.: HY-N12105CAS No.: 1015175-06-0Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside is an anti-hepatitis B virus (anti-HBV) agent. Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside inhibits HBV surface antigen (HBsAg) and HBV e antigen (HBeAg) secretion on Hep G2.2.15 cell line, with IC50 values of 1.67 and >2.15 mM, respectively.
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HBV/HDV-IN-5
0 ImagesCat. No.: HY-174297CAS No.: 103528-66-1HBV/HDV-IN-5 (example 4) is an inhibitor of hepatitis B virus (HBV) and hepatitis D virus (HDV).
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Cleruvirsen
0 ImagesCat. No.: HY-185923CAS No.: 3072046-94-4Cleruvirsen is a hepatitis B virus surface antigen (HBsAg) inhibitor with anti-hepatitis B virus (HBV) activity. Cleruvirsen can be used for hepatitis B-related research[1].
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Bifendate (Standard)
0 ImagesSynonyms: DDB (Standard)Bifendate (DDB), extracted from Schisandrae chinensis, is an orally active anti-HBV agent against chronic hepatitis B. Bifendate inhibits ATG5-dependent autophagy and attenuates oleic acid-induced lipid accumulation with anti-oxidant properties in vitro. Bifendate can decrease alanine transaminase (ALT) level in mice. Bifendate attenuates hepatic steatosis in cholesterol/bile salt- and high-fat diet-induced hypercholesterolemia in mice. Bifendate potently increases the activity of cytochrome proteins (CYPs) and reverse P-gp-mediated multi-drug resistance (MDR).
