Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11128)
Related Products (11128)
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3',5'-Di-p-toluate Thymidine-13C,15N2
0 ImagesCat. No.: HY-W7500353',5'-Di-p-toluate Thymidine-13C,15N2 is the 13C- and 15N-labeled 3',5'-Di-p-toluate Thymidine.
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D-Fructose-18O-2
0 ImagesCat. No.: HY-N7092S21Synonyms: D(-)-Fructose-18O-2D-Fructose-18O-2 is the 18O labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
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Fmoc-L-Val-OH-13C5
0 ImagesCat. No.: HY-I1111S3Synonyms: FMOC-L-valine-13C5; Fmoc-valine-13C5
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D-erythro-Sphingosine-13C2,d2
0 ImagesCat. No.: HY-101047S1CAS No.: 2692623-81-5Synonyms: Erythrosphingosine-13C2,d2; erythro-C18-Sphingosine-13C2,d2; trans-4-Sphingenine-13C2,d2D-erythro-Sphingosine-13C2,d2 is a deuterated labeled D-erythro-Sphingosine. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator.
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Maresin 1-d5
0 ImagesCat. No.: HY-116429SMaresin 1-d5 is the deuterium labeled Maresin 1. Maresin 1, produced by human Mφs from endogenous docosahexaenoic acid (DHA) and a specialized proresolving mediator, stimulates intracellular [Ca2+] and secretion. Maresin 1 possesses anti-inflammatory activity.
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Sodium (S)-2-(hydroxymethyl)propanoate-3,3,3-d3
0 ImagesCat. No.: HY-W719170Sodium (S)-2-(hydroxymethyl)propanoate-3,3,3-d3 is the deuterium labeled Sodium (S)-2-(hydroxymethyl)propanoate.
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Megestrol-d5
0 ImagesCat. No.: HY-B1834S1Megestrol-d5 is the deuterium labeled Megestrol. Megestrol is an orally active glucocorticoid and progesterone receptor agonist. Megestrol can alleviate anorexia, cachexia or unexplained significant weight loss associated with acquired immunodeficiency syndrome (AIDS). Megestrol may cause glucocorticoid-like effects and an increased risk of mental disorders.
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α-Zearalenol-13C18
0 ImagesCat. No.: HY-N6710S1α-Zearalenol-13C18 is the 13C-labeled α-Zearalenol. α-Zearalenol is a Mycotoxin with high affinity for the estrogen receptors (ER). α-Zearalenol is the derivative of zearalenone (ZEN), causes reproductive disorders in animals, due to its xenoestrogenic effects.
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Enniatin A1-13C35
0 ImagesCat. No.: HY-N6704SEnniatin A1-13C35 is the 13C-labeled Enniatin A1 (HY-N6704). Enniatin A1 isolated from Fusarium mycotoxins is a cyclic hexadepsipeptide consisting of alternating D-α-hydroxyisovaleric acids and N-methyl-L-amino acids. Enniatin A1 possesses anticarcinogenic properties by induction of apoptosis and disruption of ERK signalling pathway. Enniatin A1 inhibits ACAT with an IC50 of 49 μM in rat liver microsomes.
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Propylparaben-d7
0 ImagesCat. No.: HY-N2026SCAS No.: 1246820-92-7Synonyms: Propyl parahydroxybenzoate-d7; Propyl 4-hydroxybenzoate-d7Propylparaben-d7 (Propyl parahydroxybenzoate-d7) is the deuterium labeled Propylparaben (HY-N2026). Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is an orally active weak estrogen receptor agonist. Propylparaben regulates the PI3K-AKT and JNK signaling pathways, and induces oxidative stress. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods, and can be used in studies related to ovarian aging and myocardial ischemia-reperfusion injury.
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Baloxavir-d5
0 ImagesCat. No.: HY-109025ASSynonyms: Baloxavir acid-d5; S-033447-d5Baloxavir-d5 is deuterium labeled Baloxavir. Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity.
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1α,25-Dihydroxy-3-epi-vitamin D2--d9
0 ImagesCat. No.: HY-W783875SCAS No.: 1202355-88-11α,25-Dihydroxy-3-epi-vitamin D2-d9 is the deuterium labeled 1α,25-Dihydroxy-3-epi-vitamin D2.
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N-Arachidonyldopamine-d8
0 ImagesCat. No.: HY-110018SCAS No.: 1159908-42-5N-Arachidonyldopamine-d8 is the deuterium labeled N-Arachidonyldopamine.
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4-Hydroxy triamterene sulfate-d4 sodium
0 ImagesCat. No.: HY-142641S4-Hydroxy triamterene sulfate-d4 (sodium) is the deuterium labeled 4-Hydroxy triamterene sulfate sodium.
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D-Lysine-d4 monohydrochloride
0 ImagesCat. No.: HY-Y1804SCAS No.: 2714413-18-8D-Lysine-d4 monohydrochloride is the d4 D-Lysine monohydrochloride (HY-Y1804). D-Lysine monohydrochloride is the D-enantiomer of L-Lysine (HY-N0469). D-Lysine monohydrochloride is metabolically inert and not utilized for protein synthesis by mammalian ribosomes. D-Lysine monohydrochloride blocks renal uptake of 111In/90Y-Octreotide (HY-P0036)-based probes without inhibiting uptake by tumor/receptor tissues, and thus acts as a renoprotective agent in diagnostic imaging and peptide receptor radionuclide therapy (PRRT). D-Lysine monohydrochloride specifically inhibits the early steps of non-enzymatic glycation by competing with glucose via its free amino group, theoretically, it can serve as a glycation competitor that "does not interfere with protein synthesis" under chronic hyperglycemia in diabetes. D-Lysine monohydrochloride can be used in research related to cancer and diabetes.
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1,4-Dibromobutane-2,2,3,3-d4
0 ImagesCat. No.: HY-Y0350SCAS No.: 52089-63-11,4-Dibromobutane-2,2,3,3-d4 is the deuterium labeled 1,4-Dibromobutane.
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Tizanidine-d4 hydrochloride
0 ImagesCat. No.: HY-B0194ASCAS No.: 1188263-51-5Tizanidine-d4 hydrochloride is deuterium labeled Tizanidine hydrochloride (HY-B0194A). Tizanidine hydrochloride, a skeletal muscle relaxant, is an orally effective central α2-adrenoceptor agonist (IC50 = 6.9 nmol). Tizanidine hydrochloride primarily exerts muscle relaxation effects by inhibiting the release of excitatory amino acids (glutamate and aspartate) from the presynaptic terminals of spinal cord interneurons. Tizanidine hydrochloride has anti-injury activity and can inhibit gastrointestinal (GI) transport. Tizanidine hydrochloride can inhibit the proliferation, migration, and invasion of lung cancer cells and induce cell apoptosis by upregulating Nischarin and inhibiting the AKT and Wnt3a/β-catenin signaling pathways. Tizanidine hydrochloride can be used to treat spasticity caused by diseases such as multiple sclerosis (MS), stroke, and spinal cord injury (SCI).
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Cobicistat-d8
0 ImagesCat. No.: HY-10493SCAS No.: 2699607-48-0Synonyms: GS-9350-d8Cobicistat-d8 (GS-9350-d8) is a deuterated version of Cobicistat (HY-10493). Cobicistat is a potent and selective inhibitor of cytochrome P450 3A (CYP3A) with IC50 values of 30-285 nM. Cobicistat is a pharmacokinetic enhancer that enhances the absorption of anti-HIV active molecules.
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dGTP-15N5,d14 dilithium
0 ImagesCat. No.: HY-138616S2Synonyms: 2'-Deoxyguanosine-5'-triphosphate-15N5,d14 dilithiumdGTP-15N5,d14 (2'-Deoxyguanosine-5'-triphosphate-15N5,d14) dilithium is deuterium and 15N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
